Advertisement
Research Article

The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions

  • Cedric Montanier equal contributor,

    equal contributor Contributed equally to this work with: Cedric Montanier, Victoria A Money

    Affiliation: Institute for Cell and Molecular Biosciences, Newcastle University, The Medical School, Newcastle upon Tyne, United Kingdom

    X
  • Victoria A Money equal contributor,

    equal contributor Contributed equally to this work with: Cedric Montanier, Victoria A Money

    Affiliation: York Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York, United Kingdom

    X
  • Virginia M. R Pires,

    Affiliation: CIISA - Faculdade de Medicina Veterinária, Universidade Técnica de Lisboa, Avenida da Universidade Técnica, Lisboa, Portugal

    X
  • James E Flint,

    Affiliation: Institute for Cell and Molecular Biosciences, Newcastle University, The Medical School, Newcastle upon Tyne, United Kingdom

    X
  • Benedita A Pinheiro,

    Affiliation: CIISA - Faculdade de Medicina Veterinária, Universidade Técnica de Lisboa, Avenida da Universidade Técnica, Lisboa, Portugal

    X
  • Arun Goyal,

    Affiliation: CIISA - Faculdade de Medicina Veterinária, Universidade Técnica de Lisboa, Avenida da Universidade Técnica, Lisboa, Portugal

    X
  • José A. M Prates,

    Affiliation: CIISA - Faculdade de Medicina Veterinária, Universidade Técnica de Lisboa, Avenida da Universidade Técnica, Lisboa, Portugal

    X
  • Atsushi Izumi,

    Affiliation: York Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York, United Kingdom

    X
  • Henrik Stålbrand,

    Affiliation: Department of Biochemistry, Center for Chemistry and Chemical Engineering, Lund University, Lund, Sweden

    X
  • Carl Morland,

    Affiliation: Institute for Cell and Molecular Biosciences, Newcastle University, The Medical School, Newcastle upon Tyne, United Kingdom

    X
  • Alan Cartmell,

    Affiliation: Institute for Cell and Molecular Biosciences, Newcastle University, The Medical School, Newcastle upon Tyne, United Kingdom

    X
  • Katarina Kolenova,

    Affiliation: Department of Biochemistry, Center for Chemistry and Chemical Engineering, Lund University, Lund, Sweden

    X
  • Evangelos Topakas,

    Affiliation: Institute for Cell and Molecular Biosciences, Newcastle University, The Medical School, Newcastle upon Tyne, United Kingdom

    X
  • Eleanor J Dodson,

    Affiliation: York Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York, United Kingdom

    X
  • David N Bolam,

    Affiliation: Institute for Cell and Molecular Biosciences, Newcastle University, The Medical School, Newcastle upon Tyne, United Kingdom

    X
  • Gideon J Davies mail,

    To whom correspondence should be addressed. E-mail: davies@ysbl.york.ac.uk (GJD); H.J.Gilbert@ncl.ac.uk (HJG)

    Affiliation: York Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York, United Kingdom

    X
  • Carlos M. G. A Fontes,

    Affiliation: CIISA - Faculdade de Medicina Veterinária, Universidade Técnica de Lisboa, Avenida da Universidade Técnica, Lisboa, Portugal

    X
  • Harry J Gilbert mail

    To whom correspondence should be addressed. E-mail: davies@ysbl.york.ac.uk (GJD); H.J.Gilbert@ncl.ac.uk (HJG)

    Affiliation: Institute for Cell and Molecular Biosciences, Newcastle University, The Medical School, Newcastle upon Tyne, United Kingdom

    X
  • Published: March 31, 2009
  • DOI: 10.1371/journal.pbio.1000071

Reader Comments (0)

Post a new comment on this article