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Research Article

SARS-Coronavirus Replication Is Supported by a Reticulovesicular Network of Modified Endoplasmic Reticulum

  • Kèvin Knoops,

    Affiliations: Section Electron Microscopy, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands, Molecular Virology Laboratory, Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands

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  • Marjolein Kikkert,

    Affiliation: Molecular Virology Laboratory, Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands

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  • Sjoerd H. E. van den Worm,

    Affiliation: Molecular Virology Laboratory, Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands

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  • Jessika C Zevenhoven-Dobbe,

    Affiliation: Molecular Virology Laboratory, Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands

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  • Yvonne van der Meer,

    Affiliation: Molecular Virology Laboratory, Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands

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  • Abraham J Koster,

    Affiliation: Section Electron Microscopy, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands

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  • A. Mieke Mommaas,

    Affiliation: Section Electron Microscopy, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands

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  • Eric J Snijder mail

    To whom correspondence should be addressed. E-mail: e.j.snijder@lumc.nl

    Affiliation: Molecular Virology Laboratory, Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands

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  • Published: September 16, 2008
  • DOI: 10.1371/journal.pbio.0060226

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