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Research Article

Rescue of Progeria in Trichothiodystrophy by Homozygous Lethal Xpd Alleles

  • Jaan-Olle Andressoo,

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, Netherlands

    ¤a Current address: Institute of Biotechnology, University of Helsinki, Helsinki, Finland

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  • Judith Jans,

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, Netherlands

    ¤b Current address: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America

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  • Jan de Wit,

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, Netherlands

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  • Frederic Coin,

    Affiliation: Institut de Genetique et de Biologie et Cellulaire, Strasbourg, France

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  • Deborah Hoogstraten,

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, Netherlands

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  • Marieke van de Ven,

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, Netherlands

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  • Wendy Toussaint,

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, Netherlands

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  • Jan Huijmans,

    Affiliation: Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, Netherlands

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  • H. Bing Thio,

    Affiliation: Department of Dermatology, Erasmus Medical Center, Rotterdam, Netherlands

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  • Wibeke J van Leeuwen,

    Affiliation: Department of Experimental Radiology, Erasmus Medical Center, Rotterdam, Netherlands

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  • Jan de Boer,

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, Netherlands

    ¤c Current address: Institute for Biomedical Technology, University of Twente, Bilthoven, Netherlands

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  • Jean-Marc Egly,

    Affiliation: Institut de Genetique et de Biologie et Cellulaire, Strasbourg, France

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  • Jan H. J Hoeijmakers,

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, Netherlands

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  • Gijsbertus T. J van der Horst,

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, Netherlands

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  • James R Mitchell mail

    To whom correspondence should be addressed. E-mail: j.mitchell@erasmusmc.nl

    Affiliation: Medical Genetics Center, Department of Cell Biology and Genetics, Center of Biomedical Genetics, Erasmus Medical Center, Rotterdam, Netherlands

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  • Published: October 03, 2006
  • DOI: 10.1371/journal.pbio.0040322

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