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Organ Growth: Scaling the Drosophila Wing

From dwarves to giants, scaling is a universal property of animal organs, but its mechanistic basis is poorly understood. Here, Parker and Struhl identify a molecular circuit involving TOR and Yorkie that underlies scaling of the Drosophila wing. The image shows superimposed Drosophila wings from well-fed (large) and starved (small, false-colored blue) animals of the same genotype, illustrating the wing's capacity to scale dramatically in size.

Image Credit: Joseph Parker