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Polio: from Past to Present.

The background of the illustration conveys the historical picture of paralytic polio—children in iron lungs, or walking with the aid of crutches. In the foreground, we see polio vaccine development—Jonas Salk administering the Inactive Polio Vaccine, and the use of Albert Sabin's Oral Polio Vaccine. Using models to reveal the epidemiology of historical poliovirus transmission in the US, this study by Micaela Martinez-Bakker, Aaron King and Pejman Rohani reconstructs the millions of silent infections and identifies why polio epidemics are explosive, seasonal, and vary geographically. Martinez-Bakker et al.

Image Credit: Art by John Megahan.