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Editorial
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Book Review/Science in the Media
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Correction

Table of Contents | November 2005

About This Image

Retrogene movement within and betweeen chromosomes.

Approximately one new retrogene per million years has emerged on the primate lineage leading to humans. Most retrogenes were progressively recruited during primate evolution by natural and/or sexual selection to enhance male germ-line function. (See Marques et al.)

Image Credit: Cover design courtesy of Hybrid Medical Animation (www.hybridmedicalanimation.com)

Editorial

Scientific Longevity

Hemai Parthasarathy

Essay

The Cell Nucleus and Aging: Tantalizing Clues and Hopeful Promises

Paola Scaffidi, Leslie Gordon, Tom Misteli

Feature

Jump-Starting a Cellular World: Investigating the Origin of Life, from Soup to Networks

Richard Robinson

Book Review/Science in the Media

Darwin's Other Books: “Red” and “Transmutation” Notebooks, “Sketch,” “Essay,” and Natural Selection

Niles Eldredge

Primers

Motifs, Control, and Stability

John Doyle, Marie Csete

An Ideal Society? Neighbors of Diverse Origins Interact to Create and Maintain Complex Mini-Organs in the Skin

Sarah E Millar

Community Page

Linking Biodiversity Conservation and Livelihoods in India

Kartik Shanker, Ankila Hiremath, Kamal Bawa

Research Articles

Dynamic Properties of Network Motifs Contribute to Biological Network Organization

Robert J Prill, Pablo A Iglesias, Andre Levchenko

Differential Recruitment of Pre-mRNA Splicing Factors to Alternatively Spliced Transcripts In Vivo

Stephen A Mabon, Tom Misteli

Mechanism of Filament Nucleation and Branch Stability Revealed by the Structure of the Arp2/3 Complex at Actin Branch Junctions

Coumaran Egile, Isabelle Rouiller, Xiao-Ping Xu, Niels Volkmann, Rong Li, Dorit Hanein

Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle

Michael Rendl, Lisa Lewis, Elaine Fuchs

Modeling T Cell Antigen Discrimination Based on Feedback Control of Digital ERK Responses

Grégoire Altan-Bonnet, Ronald N Germain

Evolution of Mutational Robustness in an RNA Virus

Rebecca Montville, Remy Froissart, Susanna K Remold, Olivier Tenaillon, Paul E Turner

Wave-Like Spread of Ebola Zaire

Peter D Walsh, Roman Biek, Leslie A Real

The Geographic Spread of the CCR5 Δ32 HIV-Resistance Allele

John Novembre, Alison P Galvani, Montgomery Slatkin

The Case for Selection at CCR5-Δ32

Pardis C Sabeti, Emily Walsh, Steve F Schaffner, Patrick Varilly, Ben Fry, Holli B Hutcheson, Mike Cullen, Tarjei S Mikkelsen, Jessica Roy, Nick Patterson, Richard Cooper, David Reich, David Altshuler, Stephen O'Brien, Eric S Lander

Emergence of Young Human Genes after a Burst of Retroposition in Primates

Ana Claudia Marques, Isabelle Dupanloup, Nicolas Vinckenbosch, Alexandre Reymond, Henrik Kaessmann

Exploitative and Hierarchical Antagonism in a Cooperative Bacterium

Francesca Fiegna, Gregory J Velicer

Divergent Selection and the Evolution of Signal Traits and Mating Preferences

Howard D Rundle, Stephen F Chenoweth, Paul Doughty, Mark W Blows

Rapid Behavioral and Genomic Responses to Social Opportunity

Sabrina S Burmeister, Erich D Jarvis, Russell D Fernald

Temperature Regulates Transcription in the Zebrafish Circadian Clock

Kajori Lahiri, Daniela Vallone, Srinivas Babu Gondi, Cristina Santoriello, Thomas Dickmeis, Nicholas S Foulkes

Enhanced Odor Discrimination and Impaired Olfactory Memory by Spatially Controlled Switch of AMPA Receptors

Derya R Shimshek, Thorsten Bus, Jinhyun Kim, Andre Mihaljevic, Volker Mack, Peter H Seeburg, Rolf Sprengel, Andreas T Schaefer

Improvement of Tactile Discrimination Performance and Enlargement of Cortical Somatosensory Maps after 5 Hz rTMS

Martin Tegenthoff, Patrick Ragert, Burkhard Pleger, Peter Schwenkreis, Ann-Freya Förster, Volker Nicolas, Hubert R Dinse

First Observation of Tool Use in Wild Gorillas

Thomas Breuer, Mireille Ndoundou-Hockemba, Vicki Fishlock

Correction

Correction: Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases

Haitao Yang, Weiqing Xie, Xiaoyu Xue, Kailin Yang, Jing Ma, Wenxue Liang, Qi Zhao, Zhe Zhou, Duanqing Pei, John Ziebuhr, Rolf Hilgenfeld, Kwok Yung Yuen, Luet Wong, Guangxia Gao, Saijuan Chen, Zhu Chen, Dawei Ma, Mark Bartlam, Zihe Rao