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Table of Contents: October 2012

COVER

Exploring the tree of life with a fractal-based viewer.

Image Credit: James Rosindell, Imperial College London
Issue Image

The zooming concept of OneZoom, a new tree viewer, is demonstrated here with a phylogenetic tree of 5,020 mammal species. The colors of the leaves in this visualization indicate the degree to which that species is at risk from extinction according to the IUCN Red List. The blue label shows where human beings are—the only green leaf amongst a sea of red leaves. This is because we are not under threat of extinction, whereas all our closest relatives are either endangered or critically endangered. See Rosindell and Harmon (e1001406) in this issue.

Editorial

Synopses

Essay

Sequencing the Connectome

Anthony M. Zador, Joshua Dubnau, Hassana K. Oyibo, Huiqing Zhan, Gang Cao, Ian D. Peikon

Obituary

Primers

Parietal Cortex Signals Come Unstuck in Time

Erik P. Cook, Christopher C. Pack

Community Page

Research Articles

NAD+ Biosynthesis Ameliorates a Zebrafish Model of Muscular Dystrophy

Michelle F. Goody, Meghan W. Kelly, Christine J. Reynolds, Andre Khalil, Bryan D. Crawford, Clarissa A. Henry

Chemokine GPCR Signaling Inhibits β-Catenin during Zebrafish Axis Formation

Shu-Yu Wu, Jimann Shin, Diane S. Sepich, Lilianna Solnica-Krezel

Temporal Production Signals in Parietal Cortex

Blaine A. Schneider, Geoffrey M. Ghose

Generation of Functional Blood Vessels from a Single c-kit+ Adult Vascular Endothelial Stem Cell

Shentong Fang, Jing Wei, Nalle Pentinmikko, Hannele Leinonen, Petri Salven

The Molecular Basis for Recognition of CD1d/α-Galactosylceramide by a Human Non-Vα24 T Cell Receptor

Jacinto López-Sagaseta, Jennifer E. Kung, Paul B. Savage, Jenny Gumperz, Erin J. Adams