Table of Contents: September 2012

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Pollinating bees must typically visit a large number of flowers before they can return to their nest with a filled honey-stomach. They are thus faced with a challenge equivalent to the familiar “Travelling Salesman Problem”—to link multiple locations with an efficient route that minimizes travel distance. Here, bees' strategies in route optimization are quantified by tracking individuals over long distances with harmonic radar. It turns out that bees initially follow tortuous paths while exploring their environment for new food locations, but rapidly discover food sources and link them with an optimal circuit, using a simple trial-and-error algorithm. See Lihoreau et al. (e1001392) in this issue.


Unsolved Mystery

Revisiting an Old Riddle: What Determines Genetic Diversity Levels within Species?

Ellen M. Leffler, Kevin Bullaughey, Daniel R. Matute, Wynn K. Meyer, Laure Ségurel, Aarti Venkat, Peter Andolfatto, Molly Przeworski

Book Review/Science in the Media

What to Do When the Oceans Rise

Lauren-Kristine Pryzant, John F. Bruno


Inside the Mucosal Immune System

Jerry R. McGhee, Kohtaro Fujihashi

A New View of the Lethal Apoptotic Pore

Gorka Basañez, Lucian Soane, J. Marie Hardwick

Community Page

Research Articles

Radar Tracking and Motion-Sensitive Cameras on Flowers Reveal the Development of Pollinator Multi-Destination Routes over Large Spatial Scales

Mathieu Lihoreau, Nigel E. Raine, Andrew M. Reynolds, Ralph J. Stelzer, Ka S. Lim, Alan D. Smith, Juliet L. Osborne, Lars Chittka

Smooth Muscle Tension Induces Invasive Remodeling of the Zebrafish Intestine

Christoph Seiler, Gangarao Davuluri, Joshua Abrams, Fitzroy J. Byfield, Paul A. Janmey, Michael Pack

Independent Regulation of Basal Neurotransmitter Release Efficacy by Variable Ca2+ Influx and Bouton Size at Small Central Synapses

Yaroslav S. Ermolyuk, Felicity G. Alder, Christian Henneberger, Dmitri A. Rusakov, Dimitri M. Kullmann, Kirill E. Volynski

Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium

Ken S. Lau, Virna Cortez-Retamozo, Sarah R. Philips, Mikael J. Pittet, Douglas A. Lauffenburger, Kevin M. Haigis

IL-26 Is Overexpressed in Rheumatoid Arthritis and Induces Proinflammatory Cytokine Production and Th17 Cell Generation

Murielle Corvaisier, Yves Delneste, Henry Jeanvoine, Laurence Preisser, Simon Blanchard, Erwan Garo, Emmanuel Hoppe, Benjamin Barré, Maurice Audran, Béatrice Bouvard, Jean-Paul Saint-André, Pascale Jeannin

3D-SIM Super Resolution Microscopy Reveals a Bead-Like Arrangement for FtsZ and the Division Machinery: Implications for Triggering Cytokinesis

Michael P. Strauss, Andrew T. F. Liew, Lynne Turnbull, Cynthia B. Whitchurch, Leigh G. Monahan, Elizabeth J. Harry