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Table of Contents: April 2009

COVER

Putting the pieces together.

Image Credit: Jeffrey Gauthier (Salk Institute for Biological Studies).
Issue Image

An image of rod and cone photoreceptors in the primate retina is divided into several interlocking pieces. As reported in this issue of PLoS Biology (see Gauthier et al., e1000063), retinal ganglion cells perform a similar division of the visual scene represented by the photoreceptors. Each ganglion cell samples from an irregularly shaped region of space. These regions interlock like puzzle pieces to represent completely the images we see.

Synopses

Essay

How to Make Evolution-Proof Insecticides for Malaria Control

Andrew F Read, Penelope A Lynch, Matthew B Thomas

Research Articles

Accelerated Adaptive Evolution on a Newly Formed X Chromosome

Doris Bachtrog, Jeffrey D Jensen, Zhi Zhang

Reawakening Retrocyclins: Ancestral Human Defensins Active Against HIV-1

Nitya Venkataraman, Amy L Cole, Piotr Ruchala, Alan J Waring, Robert I Lehrer, Olga Stuchlik, Jan Pohl, Alexander M Cole

From Rapid Place Learning to Behavioral Performance: A Key Role for the Intermediate Hippocampus

Tobias Bast, Iain A Wilson, Menno P Witter, Richard G. M Morris

Receptive Fields in Primate Retina Are Coordinated to Sample Visual Space More Uniformly

Jeffrey L Gauthier, Greg D Field, Alexander Sher, Martin Greschner, Jonathon Shlens, Alan M Litke, E. J Chichilnisky

Specificity and Plasticity of Thalamocortical Connections in Sema6A Mutant Mice

Graham E Little, Guillermina López-Bendito, Annette E Rünker, Noelia García, Maria C Piñon, Alain Chédotal, Zoltán Molnár, Kevin J Mitchell

Sir2 Paralogues Cooperate to Regulate Virulence Genes and Antigenic Variation in Plasmodium falciparum

Christopher J Tonkin, Céline K Carret, Manoj T Duraisingh, Till S Voss, Stuart A Ralph, Mirja Hommel, Michael F Duffy, Liliana Mancio da Silva, Artur Scherf, Alasdair Ivens, Terence P Speed, James G Beeson, Alan F Cowman

Impaired Antibody Response Causes Persistence of Prototypic T Cell–Contained Virus

Andreas Bergthaler, Lukas Flatz, Admar Verschoor, Ahmed N Hegazy, Martin Holdener, Katja Fink, Bruno Eschli, Doron Merkler, Rami Sommerstein, Edit Horvath, Marylise Fernandez, André Fitsche, Beatrice M Senn, J. Sjef Verbeek, Bernhard Odermatt, Claire-Anne Siegrist, Daniel D Pinschewer

Identification of Human S100A9 as a Novel Target for Treatment of Autoimmune Disease via Binding to Quinoline-3-Carboxamides

Per Björk, Anders Björk, Thomas Vogl, Martin Stenström, David Liberg, Anders Olsson, Johannes Roth, Fredrik Ivars, Tomas Leanderson

Cryptochrome Mediates Light-Dependent Magnetosensitivity of Drosophila's Circadian Clock

Taishi Yoshii, Margaret Ahmad, Charlotte Helfrich-Förster

A Role for the PERIOD:PERIOD Homodimer in the Drosophila Circadian Clock

Johannes Landskron, Ko Fan Chen, Eva Wolf, Ralf Stanewsky

Structural and Functional Analyses of PAS Domain Interactions of the Clock Proteins Drosophila PERIOD and Mouse PERIOD2

Sven Hennig, Holger M Strauss, Katja Vanselow, Özkan Yildiz, Sabrina Schulze, Julia Arens, Achim Kramer, Eva Wolf

Target Genes of the MADS Transcription Factor SEPALLATA3: Integration of Developmental and Hormonal Pathways in the Arabidopsis Flower

Kerstin Kaufmann, Jose M Muiño, Ruy Jauregui, Chiara A Airoldi, Cezary Smaczniak, Pawel Krajewski, Gerco C Angenent

Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans

Michael E Hurwitz, Pamela J Vanderzalm, Laird Bloom, Julia Goldman, Gian Garriga, H. Robert Horvitz

A Cell Cycle Timer for Asymmetric Spindle Positioning

Erin K. McCarthy Campbell, Adam D Werts, Bob Goldstein

Self-Organization of Dynein Motors Generates Meiotic Nuclear Oscillations

Sven K Vogel, Nenad Pavin, Nicola Maghelli, Frank Jülicher, Iva M Tolić-Nørrelykke

Global Functional Atlas of Escherichia coli Encompassing Previously Uncharacterized Proteins

Pingzhao Hu, Sarath Chandra Janga, Mohan Babu, J. Javier Díaz-Mejía, Gareth Butland, Wenhong Yang, Oxana Pogoutse, Xinghua Guo, Sadhna Phanse, Peter Wong, Shamanta Chandran, Constantine Christopoulos, Anaies Nazarians-Armavil, Negin Karimi Nasseri, Gabriel Musso, Mehrab Ali, Nazila Nazemof, Veronika Eroukova, Ashkan Golshani, Alberto Paccanaro, Jack F Greenblatt, Gabriel Moreno-Hagelsieb, Andrew Emili

Proteomic Studies of a Single CNS Synapse Type: The Parallel Fiber/Purkinje Cell Synapse

Fekrije Selimi, Ileana M Cristea, Elizabeth Heller, Brian T Chait, Nathaniel Heintz

Structural Studies of the Giant Mimivirus

Chuan Xiao, Yurii G Kuznetsov, Siyang Sun, Susan L Hafenstein, Victor A Kostyuchenko, Paul R Chipman, Marie Suzan-Monti, Didier Raoult, Alexander McPherson, Michael G Rossmann

Base Excision by Thymine DNA Glycosylase Mediates DNA-Directed Cytotoxicity of 5-Fluorouracil

Christophe Kunz, Frauke Focke, Yusuke Saito, David Schuermann, Teresa Lettieri, Jim Selfridge, Primo Schär

Coordinated Movement of Cytoplasmic and Transmembrane Domains of RyR1 upon Gating

Montserrat Samsó, Wei Feng, Isaac N Pessah, P. D Allen

Correction

Correction: The Interscutularis Muscle Connectome

Ju Lu, Juan Carlos Tapia, Olivia L White, Jeff W Lichtman