Table of Contents: October 2005


Asymmetric division in bacteria.

Image Credit: Scanning electron micrograph by Jeffrey Skerker; false color by Liana Holmberg
Issue Image

A scanning electron micrograph of Caulobacter crescentus cells at 10,000x magnification. Each cell division for C. crescentus is asymmetric, generating two distinct daughter cells: a motile swarmer cell and a sessile stalked cell. A systematic dissection of the signal transduction genes controlling cell cycle progression, growth, and morphogenesis is presented in Skerker et al.


Published and Not Perished

Hemai Parthasarathy


Book Review/Science in the Media

Bringing Evo Devo to Life

Paul M Brakefield


A Path to Discovery: The Career of Maclyn McCarty

Joshua Lederberg, Emil C Gotschlich


Research Articles

Functional Genomic Analysis of C. elegans Molting

Alison R Frand, Sascha Russel, Gary Ruvkun

Recombination Hotspots and Population Structure in Plasmodium falciparum

Jianbing Mu, Philip Awadalla, Junhui Duan, Kate M McGee, Deirdre A Joy, Gilean A. T McVean, Xin-zhuan Su

Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases

Haitao Yang, Weiqing Xie, Xiaoyu Xue, Kailin Yang, Jing Ma, Wenxue Liang, Qi Zhao, Zhe Zhou, Duanqing Pei, John Ziebuhr, Rolf Hilgenfeld, Kwok Yung Yuen, Luet Wong, Guangxia Gao, Saijuan Chen, Zhu Chen, Dawei Ma, Mark Bartlam, Zihe Rao

Single-Nucleosome Mapping of Histone Modifications in S. cerevisiae

Chih Long Liu, Tommy Kaplan, Minkyu Kim, Stephen Buratowski, Stuart L Schreiber, Nir Friedman, Oliver J Rando

Two-Component Signal Transduction Pathways Regulating Growth and Cell Cycle Progression in a Bacterium: A System-Level Analysis

Jeffrey M Skerker, Melanie S Prasol, Barrett S Perchuk, Emanuele G Biondi, Michael T Laub

Drosophila Heartless Acts with Heartbroken/Dof in Muscle Founder Differentiation

Devkanya Dutta, Sanjeev Shaw, Tariq Maqbool, Hetal Pandya, K VijayRaghavan

Dynamics of SNARE Assembly and Disassembly during Sperm Acrosomal Exocytosis

Gerardo A. De Blas, Carlos M Roggero, Claudia N Tomes, Luis S Mayorga

The Period Length of Fibroblast Circadian Gene Expression Varies Widely among Human Individuals

Steven A Brown, Fabienne Fleury-Olela, Emi Nagoshi, Conrad Hauser, Cristiana Juge, Christophe A Meier, Rachel Chicheportiche, Jean-Michel Dayer, Urs Albrecht, Ueli Schibler

Cortical Sensitivity to Visual Features in Natural Scenes

Gidon Felsen, Jon Touryan, Feng Han, Yang Dan

Responses of Grassland Production to Single and Multiple Global Environmental Changes

Jeffrey S Dukes, Nona R Chiariello, Elsa E Cleland, Lisa A Moore, M. Rebecca Shaw, Susan Thayer, Todd Tobeck, Harold A Mooney, Christopher B Field


Correction: Highly Nonrandom Features of Synaptic Connectivity in Local Cortical Circuits

Sen Song, Per Jesper Sjöström, Markus Reigl, Sacha Nelson, Dmitri B Chklovskii

Correction: Traces of Archaic Mitochondrial Lineages Persist in Austronesian-Speaking Formosan Populations

Jean A Trejaut, Toomas Kivisild, Jun Hun Loo, Chien Liang Lee, Chun Lin He, Chia Jung Hsu, Zheng Yuan Lee, Marie Lin

Correction: Directed Migration of Positively Selected Thymocytes Visualized in Real Time

Colleen M Witt, Subhadip Raychaudhuri, Brian Schaefer, Arup K Chakraborty, Ellen A Robey