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Table of Contents: November 2011

COVER

Conserved reaction-coupled motions promote catalysis in enzyme cyclophilin A.

Image Credit: Arvind Ramanathan and Pratul K. Agarwal, Oak Ridge National Laboratory
Issue Image

Conserved reaction-coupled motions promote catalysis in enzyme cyclophilin A. The motions of distal enzyme loops (shown as thick colored tubes) impact the cis/trans isomerization reaction through changes in enzyme-substrate interactions. Substrate is shown as cyan sticks and the multiple conformations of the loops are shown to depict the direction of motion. See Ramanathan and Agarwal (e1001193).

Synopses

Unsolved Mystery

Perspective

Why Full Open Access Matters

Michael W. Carroll

Book Review/Science in the Media

Obituary

Primer

Community Page

Integrating Teaching and Research in Undergraduate Biology Laboratory Education

Matthew J. Kloser, Sara E. Brownell, Nona R. Chiariello, Tadashi Fukami

Research Articles

Fossilized Biophotonic Nanostructures Reveal the Original Colors of 47-Million-Year-Old Moths

Maria E. McNamara, Derek E. G. Briggs, Patrick J. Orr, Sonja Wedmann, Heeso Noh, Hui Cao

Molecular Pathogenesis of EBV Susceptibility in XLP as Revealed by Analysis of Female Carriers with Heterozygous Expression of SAP

Umaimainthan Palendira, Carol Low, Anna Chan, Andrew D. Hislop, Edwin Ho, Tri Giang Phan, Elissa Deenick, Matthew C. Cook, D. Sean Riminton, Sharon Choo, Richard Loh, Frank Alvaro, Claire Booth, H. Bobby Gaspar, Alessandro Moretta, Rajiv Khanna, Alan B. Rickinson, Stuart G. Tangye

De Novo Genesis of Enhancers in Vertebrates

Michael P. Eichenlaub, Laurence Ettwiller

Deficient Induction Response in a Xenopus Nucleocytoplasmic Hybrid

Patrick Narbonne, David E. Simpson, John B. Gurdon

Elimination of the Vesicular Acetylcholine Transporter in the Striatum Reveals Regulation of Behaviour by Cholinergic-Glutamatergic Co-Transmission

Monica S. Guzman, Xavier De Jaeger, Sanda Raulic, Ivana A. Souza, Alex X. Li, Susanne Schmid, Ravi S. Menon, Raul R. Gainetdinov, Marc G. Caron, Robert Bartha, Vania F. Prado, Marco A. M. Prado

Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer

Christopher A. Maxwell, Javier Benítez, Laia Gómez-Baldó, Ana Osorio, Núria Bonifaci, Ricardo Fernández-Ramires, Sylvain V. Costes, Elisabet Guinó, Helen Chen, Gareth J. R. Evans, Pooja Mohan, Isabel Català, Anna Petit, Helena Aguilar, Alberto Villanueva, Alvaro Aytes, Jordi Serra-Musach, Gad Rennert, Flavio Lejbkowicz, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Carla B. Ripamonti, Bernardo Bonanni, Alessandra Viel, Anna Allavena, Loris Bernard, Paolo Radice, Eitan Friedman, Bella Kaufman, Yael Laitman, Maya Dubrovsky, Roni Milgrom, Anna Jakubowska, Cezary Cybulski, Bohdan Gorski, Katarzyna Jaworska, Katarzyna Durda, Grzegorz Sukiennicki, Jan Lubiński, Yin Yao Shugart, Susan M. Domchek, Richard Letrero, Barbara L. Weber, Frans B. L. Hogervorst, Matti A. Rookus, J. Margriet Collee, Peter Devilee, Marjolijn J. Ligtenberg, Rob B. van der Luijt, Cora M. Aalfs, Quinten Waisfisz, Juul Wijnen, Cornelis E. P. van Roozendaal, Douglas F. Easton, Susan Peock, Margaret Cook, Clare Oliver, Debra Frost, Patricia Harrington, D. Gareth Evans, Fiona Lalloo, Rosalind Eeles, Louise Izatt, Carol Chu, Diana Eccles, Fiona Douglas, Carole Brewer, Heli Nevanlinna, Tuomas Heikkinen, Fergus J. Couch, Noralane M. Lindor, Xianshu Wang, Andrew K. Godwin, Maria A. Caligo, Grazia Lombardi, Niklas Loman, Per Karlsson, Hans Ehrencrona, Anna von Wachenfeldt, Rosa Bjork Barkardottir, Ute Hamann, Muhammad U. Rashid, Adriana Lasa, Trinidad Caldés, Raquel Andrés, Michael Schmitt, Volker Assmann, Kristen Stevens, Kenneth Offit, João Curado, Hagen Tilgner, Roderic Guigó, Gemma Aiza, Joan Brunet, Joan Castellsagué, Griselda Martrat, Ander Urruticoechea, Ignacio Blanco, Laima Tihomirova, David E. Goldgar, Saundra Buys, Esther M. John, Alexander Miron, Melissa Southey, Mary B. Daly, Rita K. Schmutzler, Barbara Wappenschmidt, Alfons Meindl, Norbert Arnold, Helmut Deissler, Raymonda Varon-Mateeva, Christian Sutter, Dieter Niederacher, Evgeny Imyamitov, Olga M. Sinilnikova, Dominique Stoppa-Lyonne, Sylvie Mazoyer, Carole Verny-Pierre, Laurent Castera, Antoine de Pauw, Yves-Jean Bignon, Nancy Uhrhammer, Jean-Philippe Peyrat, Philippe Vennin, Sandra Fert Ferrer, Marie-Agnès Collonge-Rame, Isabelle Mortemousque, Amanda B. Spurdle, Jonathan Beesley, Xiaoqing Chen, Sue Healey, Mary Helen Barcellos-Hoff, Marc Vidal, Stephen B. Gruber, Conxi Lázaro, Gabriel Capellá, Lesley McGuffog, Katherine L. Nathanson, Antonis C. Antoniou, Georgia Chenevix-Trench, Markus C. Fleisch, Víctor Moreno, Miguel Angel Pujana , HEBON, EMBRACE, SWE-BRCA, BCFR, GEMO Study Collaborators, kConFab

Unique Interplay between Sugar and Lipid in Determining the Antigenic Potency of Bacterial Antigens for NKT Cells

Enrico Girardi, Esther Dawen Yu, Yali Li, Norihito Tarumoto, Bo Pei, Jing Wang, Petr Illarionov, Yuki Kinjo, Mitchell Kronenberg, Dirk M. Zajonc

Cryo-Electron Tomography of Marburg Virus Particles and Their Morphogenesis within Infected Cells

Tanmay A. M. Bharat, James D. Riches, Larissa Kolesnikova, Sonja Welsch, Verena Krähling, Norman Davey, Marie-Laure Parsy, Stephan Becker, John A. G. Briggs

Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency

Haleh Rafati, Maribel Parra, Shweta Hakre, Yuri Moshkin, Eric Verdin, Tokameh Mahmoudi

Copy Number Variation of KIR Genes Influences HIV-1 Control

Kimberly Pelak, Anna C. Need, Jacques Fellay, Kevin V. Shianna, Sheng Feng, Thomas J. Urban, Dongliang Ge, Andrea De Luca, Javier Martinez-Picado, Steven M. Wolinsky, Jeremy J. Martinson, Beth D. Jamieson, Jay H. Bream, Maureen P. Martin, Persephone Borrow, Norman L. Letvin, Andrew J. McMichael, Barton F. Haynes, Amalio Telenti, Mary Carrington, David B. Goldstein, Galit Alter , on behalf of NIAID Center for HIV/AIDS Vaccine Immunology (CHAVI)

Electrostatically Biased Binding of Kinesin to Microtubules

Barry J. Grant, Dana M. Gheorghe, Wenjun Zheng, Maria Alonso, Gary Huber, Maciej Dlugosz, J. Andrew McCammon, Robert A. Cross