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Table of Contents: February 2010

COVER

The pea aphid Acyrthosiphon pisum, an emerging genomic model organism.

Image Credit: Shipher Wu (photograph) and Gee-way Lin (aphid provision), National Taiwan University.
Issue Image

Pea aphids extracting sap from the stem and leaves of garden peas. Nymph aphids surrounding the mother aphid were produced parthenogenetically and viviparously; sexual reproduction can be induced by shorter amounts of daylight. A study conducted by The International Aphid Genomics Consortium (e1000313) reveals significant features of the whole genome sequence of the pea aphid, shedding light on its unusual life cycle and interaction with endosymbiotic bacteria.

Synopses

Essay

Book Review/Science in the Media

Why We Conform

Julia Fischer

Primers

Community Page

VertNet: A New Model for Biodiversity Data Sharing

Heather Constable, Robert Guralnick, John Wieczorek, Carol Spencer, A. Townsend Peterson , The VertNet Steering Committee

Research Articles

Regulatory T Cells and Human Myeloid Dendritic Cells Promote Tolerance via Programmed Death Ligand-1

Shoba Amarnath, Carliann M. Costanzo, Jacopo Mariotti, Jessica L. Ullman, William G. Telford, Veena Kapoor, James L. Riley, Bruce L. Levine, Carl H. June, Timothy Fong, Noel L. Warner, Daniel H. Fowler

Shape Invariant Coding of Motion Direction in Somatosensory Cortex

Yu-Cheng Pei, Steven S. Hsiao, James C. Craig, Sliman J. Bensmaia

Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth

Anita B. Hjelmeland, Qiulian Wu, Sarah Wickman, Christine Eyler, John Heddleston, Qing Shi, Justin D. Lathia, Jennifer MacSwords, Jeongwu Lee, Roger E. McLendon, Jeremy N. Rich

Genome Sequence of the Pea Aphid Acyrthosiphon pisum

The International Aphid Genomics Consortium

Expression in Aneuploid Drosophila S2 Cells

Yu Zhang, John H. Malone, Sara K. Powell, Vipul Periwal, Eric Spana, David M. MacAlpine, Brian Oliver

The Wnt Pathway Controls Cell Death Engulfment, Spindle Orientation, and Migration through CED-10/Rac

Juan Cabello, Lukas J. Neukomm, Ufuk Günesdogan, Katharina Burkart, Steve J. Charette, Günter Lochnit, Michael O. Hengartner, Ralf Schnabel

BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules

Ting-Ting Hong, James W. Smyth, Danchen Gao, Kevin Y. Chu, Jacob M. Vogan, Tina S. Fong, Brian C. Jensen, Henry M. Colecraft, Robin M. Shaw

Voltage-Dependent Gating in a “Voltage Sensor-Less” Ion Channel

Harley T. Kurata, Markus Rapedius, Marc J. Kleinman, Thomas . Baukrowitz, Colin G. Nichols

Using Structural Information to Change the Phosphotransfer Specificity of a Two-Component Chemotaxis Signalling Complex

Christian H. Bell, Steven L. Porter, Annabel Strawson, David I. Stuart, Judith P. Armitage

mRNA Secondary Structures Fold Sequentially But Exchange Rapidly In Vivo

Elisabeth M. Mahen, Peter Y. Watson, Joseph W. Cottrell, Martha J. Fedor