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Table of Contents: January 2009

COVER

An infant chimpanzee.

Image Credit: Owen Booth
Issue Image

Many of the differences between humans and our closest living relative are likely to be the result of natural selection acting on genes. However, a nonadaptive process unrelated to natural selection may have driven evolution in some of the genes that have changed the most since our common ancestor with chimpanzees (see Berglund et al., e1000026).

Synopsis

Essays

Input Subsidies to Improve Smallholder Maize Productivity in Malawi: Toward an African Green Revolution

Glenn Denning, Patrick Kabambe, Pedro Sanchez, Alia Malik, Rafael Flor, Rebbie Harawa, Phelire Nkhoma, Colleen Zamba, Clement Banda, Chrispin Magombo, Michael Keating, Justine Wangila, Jeffrey Sachs

Perspectives

Primers

Research Articles

Concatenated Analysis Sheds Light on Early Metazoan Evolution and Fuels a Modern “Urmetazoon” Hypothesis

Bernd Schierwater, Michael Eitel, Wolfgang Jakob, Hans-Jürgen Osigus, Heike Hadrys, Stephen L Dellaporta, Sergios-Orestis Kolokotronis, Rob DeSalle

Hotspots of Biased Nucleotide Substitutions in Human Genes

Jonas Berglund, Katherine S Pollard, Matthew T Webster

When Learning and Remembering Compete: A Functional MRI Study

Willem Huijbers, Cyriel M Pennartz, Roberto Cabeza, Sander M Daselaar

A Point Mutation in the Hair Cell Nicotinic Cholinergic Receptor Prolongs Cochlear Inhibition and Enhances Noise Protection

Julian Taranda, Stéphane F Maison, Jimena A Ballestero, Eleonora Katz, Jessica Savino, Douglas E Vetter, Jim Boulter, M. Charles Liberman, Paul A Fuchs, A. Belén Elgoyhen

Cell Lineages and the Logic of Proliferative Control

Arthur D Lander, Kimberly K Gokoffski, Frederic Y. M Wan, Qing Nie, Anne L Calof

Collective Cell Migration Drives Morphogenesis of the Kidney Nephron

Aleksandr Vasilyev, Yan Liu, Sudha Mudumana, Steve Mangos, Pui-Ying Lam, Arindam Majumdar, Jinhua Zhao, Kar-Lai Poon, Igor Kondrychyn, Vladimir Korzh, Iain A Drummond

Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells

Donatella Valdembri, Patrick T Caswell, Kurt I Anderson, Juliane P Schwarz, Ireen König, Elena Astanina, Francesca Caccavari, Jim C Norman, Martin J Humphries, Federico Bussolino, Guido Serini

A Novel Function for Fragile X Mental Retardation Protein in Translational Activation

Elias G Bechara, Marie Cecile Didiot, Mireille Melko, Laetitia Davidovic, Mounia Bensaid, Patrick Martin, Marie Castets, Philippe Pognonec, Edouard W Khandjian, Hervé Moine, Barbara Bardoni

Functional Anatomy of Polycomb and Trithorax Chromatin Landscapes in Drosophila Embryos

Bernd Schuettengruber, Mythily Ganapathi, Benjamin Leblanc, Manuela Portoso, Rami Jaschek, Bas Tolhuis, Maarten van Lohuizen, Amos Tanay, Giacomo Cavalli

An Endoribonuclease Functionally Linked to Perinuclear mRNP Quality Control Associates with the Nuclear Pore Complexes

Michal Skružný, Claudia Schneider, Attila Rácz, Julan Weng, David Tollervey, Ed Hurt

The Influence of Catalysis on Mad2 Activation Dynamics

Marco Simonetta, Romilde Manzoni, Roberto Mosca, Marina Mapelli, Lucia Massimiliano, Martin Vink, Bela Novak, Andrea Musacchio, Andrea Ciliberto

Correction

Correction: Caldendrin–Jacob: A Protein Liaison That Couples NMDA Receptor Signalling to the Nucleus

Daniela C Dieterich, Anna Karpova, Marina Mikhaylova, Irina Zdobnova, Imbritt König, Marco Landwehr, Martin Kreutz, Karl-Heinz Smalla, Karin Richter, Peter Landgraf, Carsten Reissner, Tobias M Boeckers, Werner Zuschratter, Christina Spilker, Constanze I Seidenbecher, Craig C Garner, Eckart D Gundelfinger, Michael R Kreutz