Table of Contents: March 2004


The endosymbiotic bacteria Wolbachia in an insect cell line.

Image Credit: Cover image provided by Kelly Johnston and Mark Taylor, Liverpool School of Tropical Medicine
Issue Image

Endosymbiosis is an interdependent association between two species, in which one, typically microbial, partner lives within a host. Jonathan Eisen and colleagues describe the genome sequence of the endosymbiont Wolbachia pipientis, and discuss the insights that this provides into the ecology and evolution of endosymbiosis (see article). The cover shows a micrograph of Wolbachia (green) within a cell line isolated from the Asian tiger mosquito Aedes albopictus.



Unsolved Mystery

Book Reviews/Science in the Media

Journal Club

Protein Nanomachines

Michael Strong

Community Page

Research Articles

No Evidence of Neandertal mtDNA Contribution to Early Modern Humans

David Serre, André Langaney, Mario Chech, Maria Teschler-Nicola, Maja Paunovic, Philippe Mennecier, Michael Hofreiter, Göran Possnert, Svante Pääbo

Phylogenomics of the Reproductive Parasite Wolbachia pipientis wMel: A Streamlined Genome Overrun by Mobile Genetic Elements

Martin Wu, Ling V Sun, Jessica Vamathevan, Markus Riegler, Robert Deboy, Jeremy C Brownlie, Elizabeth A McGraw, William Martin, Christian Esser, Nahal Ahmadinejad, Christian Wiegand, Ramana Madupu, Maureen J Beanan, Lauren M Brinkac, Sean C Daugherty, A. Scott Durkin, James F Kolonay, William C Nelson, Yasmin Mohamoud, Perris Lee, Kristi Berry, M. Brook Young, Teresa Utterback, Janice Weidman, William C Nierman, Ian T Paulsen, Karen E Nelson, Hervé Tettelin, Scott L O'Neill, Jonathan A Eisen

Circulation and Chemotaxis of Fetal Hematopoietic Stem Cells

Julie L Christensen, Douglas E Wright, Amy J Wagers, Irving L Weissman

A Spontaneous, Recurrent Mutation in Divalent Metal Transporter-1 Exposes a Calcium Entry Pathway

Haoxing Xu, Jie Jin, Louis J DeFelice, Nancy C Andrews, David E Clapham

N-Terminal Phosphorylation of the Dopamine Transporter Is Required for Amphetamine-Induced Efflux

Habibeh Khoshbouei, Namita Sen, Bipasha Guptaroy, L'Aurelle Johnson, David Lund, Margaret E Gnegy, Aurelio Galli, Jonathan A Javitch