Table of Contents: September 2015


Sea Urchin Maternal Gene Breaks Radial Symmetry

Image Credit: Emmanuel Haillot
Issue Image

A new study by Haillot et al. reveals that Panda—a member of the TGF-β family of signaling molecule—is encoded by maternal mRNA and helps to break radial symmetry and orient the dorsal-ventral axis of the developing sea urchin embryo. The image shows 48-hour-old embryos rendered deficient for panda but then rescued by local injection of panda mRNA at the 2-cell stage. An antisense morpholino oligonucleotide targeting panda was first injected into the egg (red color), and then panda mRNA was injected into one blastomere at the 2-cell stage. Local expression of Panda (green color) rescues dorsal-ventral polarity and imposes a dorsal identity on the cells.


The Fitness Effects of Love

Roland G. Roberts


Resolving Conflicts between Agriculture and the Natural Environment

Andrew J. Tanentzap, Anthony Lamb, Susan Walker, Andrew Farmer


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Centre of the Cell: Science Comes to Life

Frances Balkwill, Katie Chambers

Research Articles

Evolutionary Trade-Offs Underlie the Multi-faceted Virulence of Staphylococcus aureus

Maisem Laabei, Anne-Catrin Uhlemann, Franklin D. Lowy, Eloise D. Austin, Maho Yokoyama, Khadija Ouadi, Edward Feil, Harry A. Thorpe, Barnabas Williams, Mark Perkins, Sharon J. Peacock, Stephen R. Clarke, Janina Dordel, Matthew Holden, Antonina A. Votintseva, Rory Bowden, Derrick W. Crook, Bernadette C. Young, Daniel J. Wilson, Mario Recker, Ruth C. Massey

BOLD Response Selective to Flow-Motion in Very Young Infants

Laura Biagi, Sofia Allegra Crespi, Michela Tosetti, Maria Concetta Morrone

Shifts of Gamma Phase across Primary Visual Cortical Sites Reflect Dynamic Stimulus-Modulated Information Transfer

Michel Besserve, Scott C. Lowe, Nikos K. Logothetis, Bernhard Schölkopf, Stefano Panzeri

Face Patch Resting State Networks Link Face Processing to Social Cognition

Caspar M. Schwiedrzik, Wilbert Zarco, Stefan Everling, Winrich A. Freiwald

Time Adaptation Shows Duration Selectivity in the Human Parietal Cortex

Masamichi J. Hayashi, Thomas Ditye, Tokiko Harada, Maho Hashiguchi, Norihiro Sadato, Synnöve Carlson, Vincent Walsh, Ryota Kanai

HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins

Valérie Brügger, Stefanie Engler, Jorge A. Pereira, Sophie Ruff, Michael Horn, Hans Welzl, Emmanuelle Münger, Adrien Vaquié, Páris N. M. Sidiropoulos, Boris Egger, Peter Yotovski, Luis Filgueira, Christian Somandin, Tessa C. Lühmann, Maurizio D’Antonio, Teppei Yamaguchi, Patrick Matthias, Ueli Suter, Claire Jacob

The Actin Nucleator Cobl Is Controlled by Calcium and Calmodulin

Wenya Hou, Maryam Izadi, Sabine Nemitz, Natja Haag, Michael M. Kessels, Britta Qualmann

Extremely High Mutation Rate of HIV-1 In Vivo

José M. Cuevas, Ron Geller, Raquel Garijo, José López-Aldeguer, Rafael Sanjuán

Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1

Shiwen Wang, Bowen Jiang, Tengfei Zhang, Lixia Liu, Yi Wang, Yiping Wang, Xiufei Chen, Huaipeng Lin, Lisha Zhou, Yukun Xia, Leilei Chen, Chen Yang, Yue Xiong, Dan Ye, Kun-Liang Guan