Table of Contents | February 2010

About This Image

The pea aphid Acyrthosiphon pisum, an emerging genomic model organism.

Pea aphids extracting sap from the stem and leaves of garden peas. Nymph aphids surrounding the mother aphid were produced parthenogenetically and viviparously; sexual reproduction can be induced by shorter amounts of daylight. A study conducted by The International Aphid Genomics Consortium (e1000313) reveals significant features of the whole genome sequence of the pea aphid, shedding light on its unusual life cycle and interaction with endosymbiotic bacteria.

Image Credit: Shipher Wu (photograph) and Gee-way Lin (aphid provision), National Taiwan University.

Synopses

Touch Neurons Have a Good Sense of Direction

Richard Robinson

BIN1: A Protein with Great Heart

Caitlin Sedwick

Current Affairs: A Mutation's-Eye View of Voltage Gating

Mary Hoff

Essay

Paleovirology—Modern Consequences of Ancient Viruses

Michael Emerman, Harmit S. Malik

Book Review/Science in the Media

Why We Conform

Julia Fischer

Primers

Genomic Responses to Abnormal Gene Dosage: The X Chromosome Improved on a Common Strategy

Xinxian Deng, Christine M. Disteche

Living the Sweet Life: How Does a Plant Pathogenic Fungus Acquire Sugar from Plants?

Nicholas J. Talbot

Community Page

VertNet: A New Model for Biodiversity Data Sharing

Heather Constable, Robert Guralnick, John Wieczorek, Carol Spencer, A. Townsend Peterson

Research Articles

Absolute Humidity and the Seasonal Onset of Influenza in the Continental United States

Jeffrey Shaman, Virginia E. Pitzer, Cécile Viboud, Bryan T. Grenfell, Marc Lipsitch

Regulatory T Cells and Human Myeloid Dendritic Cells Promote Tolerance via Programmed Death Ligand-1

Shoba Amarnath, Carliann M. Costanzo, Jacopo Mariotti, Jessica L. Ullman, William G. Telford, Veena Kapoor, James L. Riley, Bruce L. Levine, Carl H. June, Timothy Fong, Noel L. Warner, Daniel H. Fowler

Shape Invariant Coding of Motion Direction in Somatosensory Cortex

Yu-Cheng Pei, Steven S. Hsiao, James C. Craig, Sliman J. Bensmaia

Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth

Anita B. Hjelmeland, Qiulian Wu, Sarah Wickman, Christine Eyler, John Heddleston, Qing Shi, Justin D. Lathia, Jennifer MacSwords, Jeongwu Lee, Roger E. McLendon, Jeremy N. Rich

Genome Sequence of the Pea Aphid Acyrthosiphon pisum

Expression in Aneuploid Drosophila S2 Cells

Yu Zhang, John H. Malone, Sara K. Powell, Vipul Periwal, Eric Spana, David M. MacAlpine, Brian Oliver

The Wnt Pathway Controls Cell Death Engulfment, Spindle Orientation, and Migration through CED-10/Rac

Juan Cabello, Lukas J. Neukomm, Ufuk Günesdogan, Katharina Burkart, Steve J. Charette, Günter Lochnit, Michael O. Hengartner, Ralf Schnabel

Ciprofloxacin Causes Persister Formation by Inducing the TisB toxin in Escherichia coli

Tobias Dörr, Marin Vulić, Kim Lewis

A Novel High-Affinity Sucrose Transporter Is Required for Virulence of the Plant Pathogen Ustilago maydis

Ramon Wahl, Kathrin Wippel, Sarah Goos, Jörg Kämper, Norbert Sauer

BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules

Ting-Ting Hong, James W. Smyth, Danchen Gao, Kevin Y. Chu, Jacob M. Vogan, Tina S. Fong, Brian C. Jensen, Henry M. Colecraft, Robin M. Shaw

Voltage-Dependent Gating in a “Voltage Sensor-Less” Ion Channel

Harley T. Kurata, Markus Rapedius, Marc J. Kleinman, Thomas . Baukrowitz, Colin G. Nichols

Using Structural Information to Change the Phosphotransfer Specificity of a Two-Component Chemotaxis Signalling Complex

Christian H. Bell, Steven L. Porter, Annabel Strawson, David I. Stuart, Judith P. Armitage

mRNA Secondary Structures Fold Sequentially But Exchange Rapidly In Vivo

Elisabeth M. Mahen, Peter Y. Watson, Joseph W. Cottrell, Martha J. Fedor