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Table of Contents: August 2013

COVER

The evolutionary history of snake sex-chromosomes

Image Credit: Steve Jurvetson
Issue Image

Sequencing of the genomes and transcriptomes of a garter snake, a rattlesnake, and a boa leads to the first high-resolution analysis of snake sex-chromosome evolution. See Vicoso et al. (e1001643) in this issue.

Essay

Book Review/Science in the Media

The Passion Principle

Daniel Simberloff

Community Page

The COMBREX Project: Design, Methodology, and Initial Results

Brian P. Anton, Yi-Chien Chang, Peter Brown, Han-Pil Choi, Lina L. Faller, Jyotsna Guleria, Zhenjun Hu, Niels Klitgord, Ami Levy-Moonshine, Almaz Maksad, Varun Mazumdar, Mark McGettrick, Lais Osmani, Revonda Pokrzywa, John Rachlin, Rajeswari Swaminathan, Benjamin Allen, Genevieve Housman, Caitlin Monahan, Krista Rochussen, Kevin Tao, Ashok S. Bhagwat, Steven E. Brenner, Linda Columbus, Valérie de Crécy-Lagard, Donald Ferguson, Alexey Fomenkov, Giovanni Gadda, Richard D. Morgan, Andrei L. Osterman, Dmitry A. Rodionov, Irina A. Rodionova, Kenneth E. Rudd, Dieter Söll, James Spain, Shuang-yong Xu, Alex Bateman, Robert M. Blumenthal, J. Martin Bollinger, Woo-Suk Chang, Manuel Ferrer, Iddo Friedberg, Michael Y. Galperin, Julien Gobeill, Daniel Haft, John Hunt, Peter Karp, William Klimke, Carsten Krebs, Dana Macelis, Ramana Madupu, Maria J. Martin, Jeffrey H. Miller, Claire O'Donovan, Bernhard Palsson, Patrick Ruch, Aaron Setterdahl, Granger Sutton, John Tate, Alexander Yakunin, Dmitri Tchigvintsev, Germán Plata, Jie Hu, Russell Greiner, David Horn, Kimmen Sjölander, Steven L. Salzberg, Dennis Vitkup, Stanley Letovsky, Daniel Segrè, Charles DeLisi, Richard J. Roberts, Martin Steffen, Simon Kasif

Research Articles

Effects of Diet on Resource Utilization by a Model Human Gut Microbiota Containing Bacteroides cellulosilyticus WH2, a Symbiont with an Extensive Glycobiome

Nathan P. McNulty, Meng Wu, Alison R. Erickson, Chongle Pan, Brian K. Erickson, Eric C. Martens, Nicholas A. Pudlo, Brian D. Muegge, Bernard Henrissat, Robert L. Hettich, Jeffrey I. Gordon

Developmental Changes in the in Vitro Activated Regenerative Activity of Primitive Mammary Epithelial Cells

Maisam Makarem, Nagarajan Kannan, Long V. Nguyen, David J. H. F. Knapp, Sneha Balani, Michael D. Prater, John Stingl, Afshin Raouf, Oksana Nemirovsky, Peter Eirew, Connie J. Eaves

Reduced Juvenile Long-Term Depression in Tuberous Sclerosis Complex Is Mitigated in Adults by Compensatory Recruitment of mGluR5 and Erk Signaling

Wyatt B. Potter, Trina Basu, Kenneth J. O'Riordan, Allison Kirchner, Paul Rutecki, Corinna Burger, Avtar Roopra

The CK2 Kinase Stabilizes CLOCK and Represses Its Activity in the Drosophila Circadian Oscillator

Áron Szabó, Christian Papin, Daniela Zorn, Prishila Ponien, Frank Weber, Thomas Raabe, François Rouyer

Stable T-bet+GATA-3+ Th1/Th2 Hybrid Cells Arise In Vivo, Can Develop Directly from Naive Precursors, and Limit Immunopathologic Inflammation

Michael Peine, Sebastian Rausch, Caroline Helmstetter, Anja Fröhlich, Ahmed N. Hegazy, Anja A. Kühl, Christoph G. Grevelding, Thomas Höfer, Susanne Hartmann, Max Löhning

Par-1 Regulates Tissue Growth by Influencing Hippo Phosphorylation Status and Hippo-Salvador Association

Hong-Ling Huang, Shimin Wang, Meng-Xin Yin, Liang Dong, Chao Wang, Wei Wu, Yi Lu, Miao Feng, Chuanyang Dai, Xiaocan Guo, Li Li, Bin Zhao, Zhaocai Zhou, Hongbin Ji, Jin Jiang, Yun Zhao, Xin-Yuan Liu, Lei Zhang

Sonic Hedgehog Promotes Tumor Cell Survival by Inhibiting CDON Pro-Apoptotic Activity

Céline Delloye-Bourgeois, Benjamin Gibert, Nicolas Rama, Jean-Guy Delcros, Nicolas Gadot, Jean-Yves Scoazec, Robert Krauss, Agnès Bernet, Patrick Mehlen

MYRF Is a Membrane-Associated Transcription Factor That Autoproteolytically Cleaves to Directly Activate Myelin Genes

Helena Bujalka, Matthias Koenning, Stacey Jackson, Victoria M. Perreau, Bernard Pope, Curtis M. Hay, Stanlislaw Mitew, Andrew F. Hill, Q. Richard Lu, Michael Wegner, Rajini Srinivasan, John Svaren, Melanie Willingham, Ben A. Barres, Ben Emery

Molecular Composition and Ultrastructure of the Caveolar Coat Complex

Alexander Ludwig, Gillian Howard, Carolina Mendoza-Topaz, Thomas Deerinck, Mason Mackey, Sara Sandin, Mark H. Ellisman, Benjamin J. Nichols

Linking Stochastic Fluctuations in Chromatin Structure and Gene Expression

Christopher R. Brown, Changhui Mao, Elena Falkovskaia, Melissa S. Jurica, Hinrich Boeger

The HILDA Complex Coordinates a Conditional Switch in the 3′-Untranslated Region of the VEGFA mRNA

Peng Yao, Alka A. Potdar, Partho Sarothi Ray, Sandeepa M. Eswarappa, Andrew C. Flagg, Belinda Willard, Paul L. Fox