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Table of Contents: March 2013

COVER

Assembly of a mating type gene in Tetrahymena

Image Credit: Michael J. Lawson using Circos (M. Krzywinski, http://mkweb.bcgsc.ca/circos/)
Issue Image

The germline nucleus contains a tandem array of six incomplete gene pairs (MTA and MTB), one pair for each mating type. The MTA genes have a common terminal exon (color coded), which is truncated in every gene except mating type II (blue). A complete gene is assembled by joining to the mating type II terminal exon (ribbons). Joining occurs within regions (ribbon width) delineated by polymorphic nucleotides (radial lines). The MTB genes undergo a similar process. Mating type is determined when every incomplete gene pair has been deleted and one complete gene pair remains. See Cervantes, et al., in this issue.

Synopses

A Novel Path to Obesity

Caitlin Sedwick

Essay

Neuroaesthetics and the Trouble with Beauty

Bevil R. Conway, Alexander Rehding

Perspective

Book Review

A Tale of Two Perils

Alan S. Kolok

Research Articles

Why Do Cuckolded Males Provide Paternal Care?

Ashleigh S. Griffin, Suzanne H. Alonzo, Charlie K. Cornwallis

White-Opaque Switching in Natural MTLa/α Isolates of Candida albicans: Evolutionary Implications for Roles in Host Adaptation, Pathogenesis, and Sex

Jing Xie, Li Tao, Clarissa J. Nobile, Yaojun Tong, Guobo Guan, Yuan Sun, Chengjun Cao, Aaron D. Hernday, Alexander D. Johnson, Lixin Zhang, Feng-Yan Bai, Guanghua Huang

Selecting One of Several Mating Types through Gene Segment Joining and Deletion in Tetrahymena thermophila

Marcella D. Cervantes, Eileen P. Hamilton, Jie Xiong, Michael J. Lawson, Dongxia Yuan, Michalis Hadjithomas, Wei Miao, Eduardo Orias

An Abscisic Acid-Independent Oxylipin Pathway Controls Stomatal Closure and Immune Defense in Arabidopsis

Jean-Luc Montillet, Nathalie Leonhardt, Samuel Mondy, Sylvain Tranchimand, Dominique Rumeau, Marie Boudsocq, Ana Victoria Garcia, Thierry Douki, Jean Bigeard, Christiane Laurière, Anne Chevalier, Carmen Castresana, Heribert Hirt

The Cellular and Molecular Basis of Bitter Tastant-Induced Bronchodilation

Cheng-Hai Zhang, Lawrence M. Lifshitz, Karl F. Uy, Mitsuo Ikebe, Kevin E. Fogarty, Ronghua ZhuGe

Neuronal Expression of Glucosylceramide Synthase in Central Nervous System Regulates Body Weight and Energy Homeostasis

Viola Nordström, Monja Willershäuser, Silke Herzer, Jan Rozman, Oliver von Bohlen und Halbach, Sascha Meldner, Ulrike Rothermel, Sylvia Kaden, Fabian C. Roth, Clemens Waldeck, Norbert Gretz, Martin Hrabě de Angelis, Andreas Draguhn, Martin Klingenspor, Hermann-Josef Gröne, Richard Jennemann

Secretion and Signaling Activities of Lipoprotein-Associated Hedgehog and Non-Sterol-Modified Hedgehog in Flies and Mammals

Wilhelm Palm, Marta M. Swierczynska, Veena Kumari, Monika Ehrhart-Bornstein, Stefan R. Bornstein, Suzanne Eaton

Protein Kinase Activity of Phosphoinositide 3-Kinase Regulates Cytokine-Dependent Cell Survival

Daniel Thomas, Jason A. Powell, Benjamin D. Green, Emma F. Barry, Yuefang Ma, Joanna Woodcock, Stephen Fitter, Andrew C. W. Zannettino, Stuart M. Pitson, Timothy P. Hughes, Angel F. Lopez, Peter R. Shepherd, Andrew H. Wei, Paul G. Ekert, Mark A. Guthridge

A Conserved Role for Human Nup98 in Altering Chromatin Structure and Promoting Epigenetic Transcriptional Memory

William H. Light, Jonathan Freaney, Varun Sood, Abbey Thompson, Agustina D'Urso, Curt M. Horvath, Jason H. Brickner