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Table of Contents: December 2007

COVER

A neural network model of the visual cortex.

Image Credit: Artwork by Xaq Pitkow, created using Adobe Illustrator
Issue Image

Our eyes are constantly moving, which blurs the image of the world across the retina. Shown here is a neural network model of the visual cortex that removes this motion blur by using neural connections that are matched to the statistics of eye movements (see Pitkow et al., e331).

Synopsis

Essays

Improving Science Education for Sustainable Development

Michiel van Eijck, Wolff-Michael Roth

Feature

Going against the Grain

Kendall Powell

Unsolved Mystery

Primers

Research Articles

Transglutaminase 2 Undergoes a Large Conformational Change upon Activation

Daniel M Pinkas, Pavel Strop, Axel T Brunger, Chaitan Khosla

Dosage Compensation in the Mouse Balances Up-Regulation and Silencing of X-Linked Genes

Hong Lin, Vibhor Gupta, Matthew D VerMilyea, Francesco Falciani, Jeannie T Lee, Laura P O'Neill, Bryan M Turner

The Inhibition of Polo Kinase by Matrimony Maintains G2 Arrest in the Meiotic Cell Cycle

Youbin Xiang, Satomi Takeo, Laurence Florens, Stacie E Hughes, Li-Jun Huo, William D Gilliland, Selene K Swanson, Kathy Teeter, Joel W Schwartz, Michael P Washburn, Sue L Jaspersen, R. Scott Hawley

GATA3-Driven Th2 Responses Inhibit TGF-β1–Induced FOXP3 Expression and the Formation of Regulatory T Cells

Pierre-Yves Mantel, Harmjan Kuipers, Onur Boyman, Claudio Rhyner, Nadia Ouaked, Beate Rückert, Christian Karagiannidis, Bart N Lambrecht, Rudolf W Hendriks, Reto Crameri, Cezmi A Akdis, Kurt Blaser, Carsten B Schmidt-Weber

The Signal Sequence Coding Region Promotes Nuclear Export of mRNA

Alexander F Palazzo, Michael Springer, Yoko Shibata, Chung-Sheng Lee, Anusha P Dias, Tom A Rapoport

The foxa2 Gene Controls the Birth and Spontaneous Degeneration of Dopamine Neurons in Old Age

Raja Kittappa, Wendy W Chang, Rajeshwar B Awatramani, Ronald D. G McKay

Incomplete and Inaccurate Vocal Imitation after Knockdown of FoxP2 in Songbird Basal Ganglia Nucleus Area X

Sebastian Haesler, Christelle Rochefort, Benjamin Georgi, Pawel Licznerski, Pavel Osten, Constance Scharff

Basic Math in Monkeys and College Students

Jessica F Cantlon, Elizabeth M Brannon