Table of Contents: October 2003


Borneo elephants, a genetically distinct taxon native to Borneo.

Image Credit: Photograph kindly provided by Cede Prudente, World Wildlife Fund, Malaysia
Issue Image

The cover shows native Borneo elephants, which are now recognized as genetically distinct from other Asian elephants. The Borneo elephants are therefore a high priority for conservation. (See Fernando, et al.)

Message from the Founders

Why PLoS Became a Publisher

Patrick O Brown, Michael B Eisen, Harold E Varmus


PLoS Biology—We're Open

Philip Bernstein, Barbara Cohen, Catriona MacCallum, Hemai Parthasarathy, Mark Patterson, Vivian Siegel


Neuroscience Networks

Thomas R Insel, Nora D Volkow, Ting-Kai Li, James F Battey Jr, Story C Landis


Digital Evolution

Bill O'Neill

Unsolved Mystery

Journal Club


Community Page

Out of the Way

Glenn Otis Brown

Research Articles

Drosophila Free-Running Rhythms Require Intercellular Communication

Ying Peng, Dan Stoleru, Joel D Levine, Jeffrey C Hall, Michael Rosbash

Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action

Inês Barroso, Jian'an Luan, Rita P. S Middelberg, Anne-Helen Harding, Paul W Franks, Rupert W Jakes, David Clayton, Alan J Schafer, Stephen O'Rahilly, Nicholas J Wareham

A Functional Analysis of the Spacer of V(D)J Recombination Signal Sequences

Alfred Ian Lee, Sebastian D Fugmann, Lindsay G Cowell, Leon M Ptaszek, Garnett Kelsoe, David G Schatz

Developmental Origin and Evolution of Bacteriocytes in the Aphid–Buchnera Symbiosis

Christian Braendle, Toru Miura, Ryan Bickel, Alexander W Shingleton, Srinivas Kambhampati, David L Stern

Genome-Wide RNAi of C. elegans Using the Hypersensitive rrf-3 Strain Reveals Novel Gene Functions

Femke Simmer, Celine Moorman, Alexander M van der Linden, Ewart Kuijk, Peter V.E van den Berghe, Ravi S Kamath, Andrew G Fraser, Julie Ahringer, Ronald H. A Plasterk

DNA Analysis Indicates That Asian Elephants Are Native to Borneo and Are Therefore a High Priority for Conservation

Prithiviraj Fernando, T. N. C Vidya, John Payne, Michael Stuewe, Geoffrey Davison, Raymond J Alfred, Patrick Andau, Edwin Bosi, Annelisa Kilbourn, Don J Melnick