Advertisement
Research Article

Crag Is a GEF for Rab11 Required for Rhodopsin Trafficking and Maintenance of Adult Photoreceptor Cells

  • Bo Xiong,

    Affiliation: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Vafa Bayat,

    Affiliations: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America, Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Manish Jaiswal,

    Affiliation: Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Ke Zhang,

    Affiliation: Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Hector Sandoval,

    Affiliation: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Wu-Lin Charng,

    Affiliation: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Tongchao Li,

    Affiliation: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Gabriela David,

    Affiliation: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Lita Duraine,

    Affiliation: Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Yong-Qi Lin,

    Affiliation: Neuroscience Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia

    X
  • G. Gregory Neely,

    Affiliation: Neuroscience Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia

    X
  • Shinya Yamamoto,

    Affiliations: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Hugo J. Bellen mail

    hbellen@bcm.edu

    Affiliations: Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, United States of America, Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States of America, Neurological Research Institute, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Published: December 04, 2012
  • DOI: 10.1371/journal.pbio.1001438

About the Authors

Bo Xiong, Vafa Bayat, Wu-Lin Charng, Tongchao Li, Gabriela David, Shinya Yamamoto, Hugo J. Bellen
Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America
Vafa Bayat
Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas, United States of America
Manish Jaiswal, Lita Duraine, Hugo J. Bellen
Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas, United States of America
Ke Zhang, Hugo J. Bellen
Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America
Hector Sandoval, Shinya Yamamoto, Hugo J. Bellen
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America
Yong-Qi Lin, G. Gregory Neely
Neuroscience Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
Hugo J. Bellen
Department of Neuroscience, Baylor College of Medicine, Houston, Texas, United States of America
Hugo J. Bellen
Neurological Research Institute, Baylor College of Medicine, Houston, Texas, United States of America

Corresponding Author

Email: hbellen@bcm.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: BX HJB. Performed the experiments: BX VB MJ KZ HS WLC TL GD LD SY YQL GGN. Analyzed the data: BX YQL HJB. Contributed reagents/materials/analysis tools: MJ LD SY. Wrote the paper: BX HJB.