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Research Article

Systematic Dissection of Roles for Chromatin Regulators in a Yeast Stress Response

  • Assaf Weiner equal contributor,

    equal contributor Contributed equally to this work with: Assaf Weiner, Hsiuyi V. Chen

    Affiliations: School of Computer Science and Engineering, The Hebrew University, Jerusalem, Israel, Alexander Silberman Institute of Life Sciences, The Hebrew University, Jerusalem, Israel

    X
  • Hsiuyi V. Chen equal contributor,

    equal contributor Contributed equally to this work with: Assaf Weiner, Hsiuyi V. Chen

    Affiliation: Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    X
  • Chih Long Liu,

    Affiliation: Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    X
  • Ayelet Rahat,

    Affiliations: School of Computer Science and Engineering, The Hebrew University, Jerusalem, Israel, Alexander Silberman Institute of Life Sciences, The Hebrew University, Jerusalem, Israel

    X
  • Avital Klien,

    Affiliations: School of Computer Science and Engineering, The Hebrew University, Jerusalem, Israel, Alexander Silberman Institute of Life Sciences, The Hebrew University, Jerusalem, Israel

    X
  • Luis Soares,

    Affiliation: Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Mohanram Gudipati,

    Affiliation: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

    X
  • Jenna Pfeffner,

    Affiliation: Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Aviv Regev,

    Affiliations: Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

    X
  • Stephen Buratowski,

    Affiliation: Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Jeffrey A. Pleiss,

    Affiliation: Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America

    X
  • Nir Friedman mail,

    nir@cs.huji.ac.il (NF); Oliver.Rando@umassmed.edu (OJR)

    Affiliations: School of Computer Science and Engineering, The Hebrew University, Jerusalem, Israel, Alexander Silberman Institute of Life Sciences, The Hebrew University, Jerusalem, Israel

    X
  • Oliver J. Rando mail

    nir@cs.huji.ac.il (NF); Oliver.Rando@umassmed.edu (OJR)

    Affiliation: Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    X
  • Published: July 31, 2012
  • DOI: 10.1371/journal.pbio.1001369

About the Authors

Assaf Weiner, Ayelet Rahat, Avital Klien, Nir Friedman
School of Computer Science and Engineering, The Hebrew University, Jerusalem, Israel
Assaf Weiner, Ayelet Rahat, Avital Klien, Nir Friedman
Alexander Silberman Institute of Life Sciences, The Hebrew University, Jerusalem, Israel
Hsiuyi V. Chen, Chih Long Liu, Oliver J. Rando
Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
Luis Soares, Stephen Buratowski
Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America
Mohanram Gudipati, Jeffrey A. Pleiss
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, United States of America
Jenna Pfeffner, Aviv Regev
Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America
Aviv Regev
Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: OJR NF AW HVC JP SB ARegev. Performed the experiments: HVC AW CLL LS MG. Analyzed the data: AW OJR HVC NF. Contributed reagents/materials/analysis tools: JAP ARegev AK ARahat. Wrote the paper: HVC AW NF OJR.