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Research Article

The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi

  • Victoria C. Barclay mail,

    vcb11@psu.edu

    Affiliation: Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Derek Sim,

    Affiliation: Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Brian H. K. Chan,

    Affiliation: Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Lucas A. Nell,

    Affiliation: Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Maia A. Rabaa,

    Affiliation: Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Andrew S. Bell,

    Affiliation: Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

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  • Robin F. Anders,

    Affiliation: Department of Biochemistry, La Trobe University, Melbourne, Australia

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  • Andrew F. Read

    Affiliations: Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America, Department of Entomology, The Pennsylvania State University, University Park, Pennsylvania, United States of America, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Published: July 31, 2012
  • DOI: 10.1371/journal.pbio.1001368
  • Featured in PLOS Collections

About the Authors

Victoria C. Barclay, Derek Sim, Brian H. K. Chan, Lucas A. Nell, Maia A. Rabaa, Andrew S. Bell, Andrew F. Read
Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America
Robin F. Anders
Department of Biochemistry, La Trobe University, Melbourne, Australia
Andrew F. Read
Department of Entomology, The Pennsylvania State University, University Park, Pennsylvania, United States of America
Andrew F. Read
Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America

Corresponding Author

Email: vcb11@psu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VCB AFR. Performed the experiments: VCB DS BHKC LAN ASB. Analyzed the data: VCB AFR. Contributed reagents/materials/analysis tools: RFA AFR. Wrote the paper: VCB RFA AFR. Figure S2: VCB, MAR.