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Research Article

Stochastic Expression of the Interferon-β Gene

  • Mingwei Zhao,

    Affiliation: Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • Jiangwen Zhang equal contributor,

    equal contributor Contributed equally to this work with: Jiangwen Zhang, Hemali Phatnani

    Affiliation: FAS Research Computing, Harvard University, Cambridge, Massachusetts, United States of America

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  • Hemali Phatnani equal contributor,

    equal contributor Contributed equally to this work with: Jiangwen Zhang, Hemali Phatnani

    Affiliation: Columbia University College of Physicians and Surgeons, Department of Biochemistry and Molecular Biophysics, New York, New York, United States of America

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  • Stefanie Scheu,

    Affiliation: Institute of Medical Microbiology and Hospital Hygiene, Universität Düsseldorf, Düsseldorf, Germany

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  • Tom Maniatis mail

    tm2472@mail.cumc.columbia.edu

    Affiliations: Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America, Columbia University College of Physicians and Surgeons, Department of Biochemistry and Molecular Biophysics, New York, New York, United States of America

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  • Published: January 24, 2012
  • DOI: 10.1371/journal.pbio.1001249

About the Authors

Mingwei Zhao, Tom Maniatis
Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America
Jiangwen Zhang
FAS Research Computing, Harvard University, Cambridge, Massachusetts, United States of America
Hemali Phatnani, Tom Maniatis
Columbia University College of Physicians and Surgeons, Department of Biochemistry and Molecular Biophysics, New York, New York, United States of America
Stefanie Scheu
Institute of Medical Microbiology and Hospital Hygiene, Universität Düsseldorf, Düsseldorf, Germany

Corresponding Author

Email: tm2472@mail.cumc.columbia.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: MZ HP TM. Performed the experiments: MZ. Analyzed the data: MZ JZ. Contributed reagents/materials/analysis tools: SS. Wrote the paper: MZ HP TM.