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Research Article

Mouse PRDM9 DNA-Binding Specificity Determines Sites of Histone H3 Lysine 4 Trimethylation for Initiation of Meiotic Recombination

  • Corinne Grey,

    Affiliation: Institut de Génétique Humaine, CNRS UPR 1142, Montpellier, France

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  • Pauline Barthès,

    Affiliation: Institut de Génétique Humaine, CNRS UPR 1142, Montpellier, France

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  • Gaëlle Chauveau-Le Friec,

    Affiliation: Centre d'Ingénierie Génétique Murine, Institut Pasteur, Paris, France

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  • Francina Langa,

    Affiliation: Centre d'Ingénierie Génétique Murine, Institut Pasteur, Paris, France

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  • Frédéric Baudat mail,

    frederic.baudat@igh.cnrs.fr

    Affiliation: Institut de Génétique Humaine, CNRS UPR 1142, Montpellier, France

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  • Bernard de Massy

    Affiliation: Institut de Génétique Humaine, CNRS UPR 1142, Montpellier, France

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  • Published: October 18, 2011
  • DOI: 10.1371/journal.pbio.1001176

About the Authors

Corinne Grey, Pauline Barthès, Frédéric Baudat, Bernard de Massy
Institut de Génétique Humaine, CNRS UPR 1142, Montpellier, France
Gaëlle Chauveau-Le Friec, Francina Langa
Centre d'Ingénierie Génétique Murine, Institut Pasteur, Paris, France

Corresponding Author

Email: frederic.baudat@igh.cnrs.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: CG PB FB BdM. Performed the experiments: CG PB FB. Analyzed the data: CG PB FB BdM. Contributed reagents/materials/analysis tools: GCLF FL. Wrote the paper: CG FB BdM.