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Research Article

An OBSL1-Cul7Fbxw8 Ubiquitin Ligase Signaling Mechanism Regulates Golgi Morphology and Dendrite Patterning

  • Nadia Litterman,

    Affiliations: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Program in Neuroscience, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Yoshiho Ikeuchi,

    Affiliation: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Gilbert Gallardo,

    Affiliation: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Brenda C. O'Connell,

    Affiliation: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Mathew E. Sowa,

    Affiliation: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Steven P. Gygi,

    Affiliation: Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • J. Wade Harper,

    Affiliation: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Azad Bonni mail

    azad_bonni@hms.harvard.edu

    Affiliations: Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Program in Neuroscience, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: May 10, 2011
  • DOI: 10.1371/journal.pbio.1001060

About the Authors

Nadia Litterman, Yoshiho Ikeuchi, Gilbert Gallardo, Brenda C. O'Connell, Mathew E. Sowa, J. Wade Harper, Azad Bonni
Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America
Nadia Litterman, Azad Bonni
Program in Neuroscience, Harvard Medical School, Boston, Massachusetts, United States of America
Steven P. Gygi
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America

Corresponding Author

Email: azad_bonni@hms.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: NL AB. Performed the experiments: NL YI GG BCO. Analyzed the data: NL GG BCO. Contributed reagents/materials/analysis tools: NL MES JWH SPG. Wrote the paper: NL AB.