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Research Article

Eps8 Regulates Hair Bundle Length and Functional Maturation of Mammalian Auditory Hair Cells

  • Valeria Zampini equal contributor,

    equal contributor Contributed equally to this work with: Valeria Zampini, Lukas Rüttiger, Stuart L. Johnson, Christoph Franz, David N. Furness

    Affiliations: Department of Biomedical Science, University of Sheffield, Sheffield, United Kingdom, Department of Physiology, University of Pavia, Pavia, Italy

    X
  • Lukas Rüttiger equal contributor,

    equal contributor Contributed equally to this work with: Valeria Zampini, Lukas Rüttiger, Stuart L. Johnson, Christoph Franz, David N. Furness

    Affiliation: Department of Otolaryngology, THR, University of Tübingen, Tübingen, Germany

    X
  • Stuart L. Johnson equal contributor,

    equal contributor Contributed equally to this work with: Valeria Zampini, Lukas Rüttiger, Stuart L. Johnson, Christoph Franz, David N. Furness

    Affiliation: Department of Biomedical Science, University of Sheffield, Sheffield, United Kingdom

    X
  • Christoph Franz equal contributor,

    equal contributor Contributed equally to this work with: Valeria Zampini, Lukas Rüttiger, Stuart L. Johnson, Christoph Franz, David N. Furness

    Affiliation: Department of Otolaryngology, THR, University of Tübingen, Tübingen, Germany

    X
  • David N. Furness equal contributor,

    equal contributor Contributed equally to this work with: Valeria Zampini, Lukas Rüttiger, Stuart L. Johnson, Christoph Franz, David N. Furness

    Affiliation: Institute for Science and Technology in Medicine, Keele University, Keele, United Kingdom

    X
  • Jörg Waldhaus,

    Affiliation: Department of Otolaryngology, THR, University of Tübingen, Tübingen, Germany

    X
  • Hao Xiong,

    Affiliations: Department of Otolaryngology, THR, University of Tübingen, Tübingen, Germany, Department of Otolaryngology-Head & Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China

    X
  • Carole M. Hackney,

    Affiliation: Department of Biomedical Science, University of Sheffield, Sheffield, United Kingdom

    X
  • Matthew C. Holley,

    Affiliation: Department of Biomedical Science, University of Sheffield, Sheffield, United Kingdom

    X
  • Nina Offenhauser,

    Affiliation: IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy

    X
  • Pier Paolo Di Fiore,

    Affiliations: IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy, Istituto Europeo di Oncologia, Milan, Italy, Dipartimento di Medicina, Chirurgia e Odontoiatria, Università degli Studi di Milano, Milan, Italy

    X
  • Marlies Knipper,

    Affiliation: Department of Otolaryngology, THR, University of Tübingen, Tübingen, Germany

    X
  • Sergio Masetto mail,

    w.marcotti@sheffield.ac.uk (WM); smasetto@unipv.it (SM)

    Affiliation: Department of Physiology, University of Pavia, Pavia, Italy

    X
  • Walter Marcotti mail

    w.marcotti@sheffield.ac.uk (WM); smasetto@unipv.it (SM)

    Affiliation: Department of Biomedical Science, University of Sheffield, Sheffield, United Kingdom

    X
  • Published: April 19, 2011
  • DOI: 10.1371/journal.pbio.1001048

About the Authors

Valeria Zampini, Stuart L. Johnson, Carole M. Hackney, Matthew C. Holley, Walter Marcotti
Department of Biomedical Science, University of Sheffield, Sheffield, United Kingdom
Valeria Zampini, Sergio Masetto
Department of Physiology, University of Pavia, Pavia, Italy
Lukas Rüttiger, Christoph Franz, Jörg Waldhaus, Hao Xiong, Marlies Knipper
Department of Otolaryngology, THR, University of Tübingen, Tübingen, Germany
David N. Furness
Institute for Science and Technology in Medicine, Keele University, Keele, United Kingdom
Hao Xiong
Department of Otolaryngology-Head & Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China
Nina Offenhauser, Pier Paolo Di Fiore
IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy
Pier Paolo Di Fiore
Istituto Europeo di Oncologia, Milan, Italy
Pier Paolo Di Fiore
Dipartimento di Medicina, Chirurgia e Odontoiatria, Università degli Studi di Milano, Milan, Italy

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: WM. Performed the experiments: VZ LR SLJ CF DNF JW HX CMH WM. Analyzed the data: VZ LR SLJ CF DNF JW HX CMH MCH MK WM. Contributed reagents/materials/analysis tools: NO PPDF. Wrote the paper: SM WM.