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Research Article

Direct Observation of the Myosin Va Recovery Stroke That Contributes to Unidirectional Stepping along Actin

  • Katsuyuki Shiroguchi mail,

    kshirog@fas.harvard.edu (KS); enrique.delacruz@yale.edu (EMD)

    Affiliation: Department of Physics, Faculty of Science and Engineering, Waseda University, Tokyo, Japan

    Current address: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • Harvey F. Chin,

    Affiliation: Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America

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  • Diane E. Hannemann,

    Affiliation: Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America

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  • Eiro Muneyuki,

    Affiliation: Department of Physics, Faculty of Science and Technology, Chuo University, Tokyo, Japan

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  • Enrique M. De La Cruz mail,

    kshirog@fas.harvard.edu (KS); enrique.delacruz@yale.edu (EMD)

    Affiliation: Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America

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  • Kazuhiko Kinosita Jr.

    Affiliation: Department of Physics, Faculty of Science and Engineering, Waseda University, Tokyo, Japan

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  • Published: April 12, 2011
  • DOI: 10.1371/journal.pbio.1001031

About the Authors

Katsuyuki Shiroguchi, Kazuhiko Kinosita Jr.
Department of Physics, Faculty of Science and Engineering, Waseda University, Tokyo, Japan
Harvey F. Chin, Diane E. Hannemann, Enrique M. De La Cruz
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America
Eiro Muneyuki
Department of Physics, Faculty of Science and Technology, Chuo University, Tokyo, Japan

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: KS KK. Performed the experiments: KS HFC. Analyzed the data: KS. Contributed reagents/materials/analysis tools: KS DEH EM EMDLC KK. Wrote the paper: KS EMDLC KK.