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Research Article

A Cytoplasmic Complex Mediates Specific mRNA Recognition and Localization in Yeast

  • Marisa Müller equal contributor,

    equal contributor Contributed equally to this work with: Marisa Müller, Roland Gerhard Heym

    Affiliations: Institute of Structural Biology, Helmholtz Zentrum München–German Research Center for Environmental Health, München, Germany, Gene Center and Department of Biochemistry, Ludwig-Maximilians-University, München, Germany

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  • Roland Gerhard Heym equal contributor,

    equal contributor Contributed equally to this work with: Marisa Müller, Roland Gerhard Heym

    Affiliations: Institute of Structural Biology, Helmholtz Zentrum München–German Research Center for Environmental Health, München, Germany, Gene Center and Department of Biochemistry, Ludwig-Maximilians-University, München, Germany

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  • Andreas Mayer,

    Affiliation: Gene Center and Department of Biochemistry, Ludwig-Maximilians-University, München, Germany

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  • Katharina Kramer,

    Affiliation: Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany

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  • Maria Schmid,

    Affiliation: Gene Center and Department of Biochemistry, Ludwig-Maximilians-University, München, Germany

    Current address: Roche Diagnostics GmbH, Penzberg, Germany

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  • Patrick Cramer,

    Affiliations: Gene Center and Department of Biochemistry, Ludwig-Maximilians-University, München, Germany, Center for Integrated Protein Science CIPSM, München, Germany

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  • Henning Urlaub,

    Affiliation: Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany

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  • Ralf-Peter Jansen,

    Affiliations: Gene Center and Department of Biochemistry, Ludwig-Maximilians-University, München, Germany, Interfaculty Institute for Biochemistry, University of Tübingen, Tübingen, Germany

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  • Dierk Niessing mail

    niessing@helmholtz-muenchen.de

    Affiliations: Institute of Structural Biology, Helmholtz Zentrum München–German Research Center for Environmental Health, München, Germany, Gene Center and Department of Biochemistry, Ludwig-Maximilians-University, München, Germany

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  • Published: April 19, 2011
  • DOI: 10.1371/journal.pbio.1000611

About the Authors

Marisa Müller, Roland Gerhard Heym, Dierk Niessing
Institute of Structural Biology, Helmholtz Zentrum München–German Research Center for Environmental Health, München, Germany
Marisa Müller, Roland Gerhard Heym, Andreas Mayer, Maria Schmid, Patrick Cramer, Ralf-Peter Jansen, Dierk Niessing
Gene Center and Department of Biochemistry, Ludwig-Maximilians-University, München, Germany
Katharina Kramer, Henning Urlaub
Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany
Patrick Cramer
Center for Integrated Protein Science CIPSM, München, Germany
Ralf-Peter Jansen
Interfaculty Institute for Biochemistry, University of Tübingen, Tübingen, Germany

Corresponding Author

Email: niessing@helmholtz-muenchen.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: MM RGH AM KK RPJ DN. Performed the experiments: MM RGH AM KK MS RPJ. Analyzed the data: MM RGH AM KK MS PC HU RPJ DN. Contributed reagents/materials/analysis tools: MM RGH AM KK PC HU RPJ DN. Wrote the paper: MM RGH DN.