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Research Article

Molecular Architecture of the Human Mediator–RNA Polymerase II–TFIIF Assembly

  • Carrie Bernecky,

    Affiliation: Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado, United States of America

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  • Patricia Grob,

    Affiliation: Howard Hughes Medical Institute and the Department of Molecular and Cell Biology, University of California, Berkeley, California, United States of America

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  • Christopher C. Ebmeier,

    Affiliation: Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado, United States of America

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  • Eva Nogales,

    Affiliation: Howard Hughes Medical Institute and the Department of Molecular and Cell Biology, University of California, Berkeley, California, United States of America

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  • Dylan J. Taatjes mail

    Taatjes@colorado.edu

    Affiliation: Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado, United States of America

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  • Published: March 29, 2011
  • DOI: 10.1371/journal.pbio.1000603

About the Authors

Carrie Bernecky, Christopher C. Ebmeier, Dylan J. Taatjes
Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado, United States of America
Patricia Grob, Eva Nogales
Howard Hughes Medical Institute and the Department of Molecular and Cell Biology, University of California, Berkeley, California, United States of America

Corresponding Author

Email: Taatjes@colorado.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: CB CCE DT. Performed the experiments: CB CCE. Analyzed the data: CB PG CCE EN DT. Wrote the paper: CB PG EN DT.