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Research Article

Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis

  • Marcos V. A. S. Navarro equal contributor,

    equal contributor Contributed equally to this work with: Marcos V. A. S. Navarro, Peter D. Newell, Petya V. Krasteva, Debashree Chatterjee

    Affiliation: Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

    Current address: Grupo de Biofísica Molecular Sérgio Mascarenhas, Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos, Brazil

    X
  • Peter D. Newell equal contributor,

    equal contributor Contributed equally to this work with: Marcos V. A. S. Navarro, Peter D. Newell, Petya V. Krasteva, Debashree Chatterjee

    Affiliation: Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, New Hampshire, United States of America

    X
  • Petya V. Krasteva equal contributor,

    equal contributor Contributed equally to this work with: Marcos V. A. S. Navarro, Peter D. Newell, Petya V. Krasteva, Debashree Chatterjee

    Affiliation: Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

    X
  • Debashree Chatterjee equal contributor,

    equal contributor Contributed equally to this work with: Marcos V. A. S. Navarro, Peter D. Newell, Petya V. Krasteva, Debashree Chatterjee

    Affiliation: Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

    X
  • Dean R. Madden,

    Affiliation: Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire, United States of America

    X
  • George A. O'Toole,

    Affiliation: Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, New Hampshire, United States of America

    X
  • Holger Sondermann mail

    hs293@cornell.edu

    Affiliation: Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

    X
  • Published: February 01, 2011
  • DOI: 10.1371/journal.pbio.1000588

About the Authors

Marcos V. A. S. Navarro, Petya V. Krasteva, Debashree Chatterjee, Holger Sondermann
Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
Peter D. Newell, George A. O'Toole
Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, New Hampshire, United States of America
Dean R. Madden
Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire, United States of America

Corresponding Author

Email: hs293@cornell.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: MVN PDN PVK DC DRM GAO HS. Performed the experiments: MVN PDN PVK DC DRM. Analyzed the data: MVN PDN PVK DC DRM GAO HS. Contributed reagents/materials/analysis tools: PDN GAO. Wrote the paper: PDN PVK DRM GAO HS.