Advertisement
Research Article

Evolutionary Tinkering with Conserved Components of a Transcriptional Regulatory Network

  • Hugo Lavoie,

    Affiliations: Biotechnology Research Institute, National Research Council, Montreal, Quebec, Canada, Department of Biology, McGill University, Montreal, Quebec, Canada

    Current address: Intracellular Signaling Laboratory, Institute of Research in Immunology and Cancer (IRIC), University of Montreal, Montreal, Quebec, Canada.

    X
  • Hervé Hogues,

    Affiliation: Biotechnology Research Institute, National Research Council, Montreal, Quebec, Canada

    X
  • Jaideep Mallick,

    Affiliation: Biotechnology Research Institute, National Research Council, Montreal, Quebec, Canada

    X
  • Adnane Sellam,

    Affiliations: Biotechnology Research Institute, National Research Council, Montreal, Quebec, Canada, Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, Canada

    X
  • André Nantel,

    Affiliations: Biotechnology Research Institute, National Research Council, Montreal, Quebec, Canada, Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, Canada

    X
  • Malcolm Whiteway mail

    malcolm.whiteway@cnrc-nrc.gc.ca

    Affiliations: Biotechnology Research Institute, National Research Council, Montreal, Quebec, Canada, Department of Biology, McGill University, Montreal, Quebec, Canada

    X
  • Published: March 09, 2010
  • DOI: 10.1371/journal.pbio.1000329

About the Authors

Hugo Lavoie, Hervé Hogues, Jaideep Mallick, Adnane Sellam, André Nantel, Malcolm Whiteway
Biotechnology Research Institute, National Research Council, Montreal, Quebec, Canada
Hugo Lavoie, Malcolm Whiteway
Department of Biology, McGill University, Montreal, Quebec, Canada
Adnane Sellam, André Nantel
Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, Canada

Corresponding Author

Email: malcolm.whiteway@cnrc-nrc.gc.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: HL. Performed the experiments: HL. Analyzed the data: HL HH. Wrote the paper: HL MW. Responsible for all bioinformatics analyses: HH. Developed the Fhl1-Ifh1 co-immunoprecipitations: JM. Performed microarray hybridizations: AS. Edited the manuscript: HH AN.