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Research Article

Dual Regulation by Pairs of Cyclin-Dependent Protein Kinases and Histone Deacetylases Controls G1 Transcription in Budding Yeast

  • Dongqing Huang equal contributor,

    equal contributor Contributed equally to this work with: Dongqing Huang, Supipi Kaluarachchi

    Affiliations: Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Supipi Kaluarachchi equal contributor,

    equal contributor Contributed equally to this work with: Dongqing Huang, Supipi Kaluarachchi

    Affiliations: Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Dewald van Dyk,

    Affiliations: Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Helena Friesen,

    Affiliations: Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Richelle Sopko,

    Affiliations: Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Wei Ye,

    Affiliations: Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Nazareth Bastajian,

    Affiliations: Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Jason Moffat,

    Affiliations: Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Holly Sassi,

    Affiliations: Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Michael Costanzo mail,

    michael.costanzo@utoronto.ca (MC); brenda.andrews@utoronto.ca (BJA)

    Affiliations: Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Brenda J. Andrews mail

    michael.costanzo@utoronto.ca (MC); brenda.andrews@utoronto.ca (BJA)

    Affiliations: Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

    X
  • Published: September 08, 2009
  • DOI: 10.1371/journal.pbio.1000188

About the Authors

Dongqing Huang, Supipi Kaluarachchi, Dewald van Dyk, Helena Friesen, Richelle Sopko, Wei Ye, Nazareth Bastajian, Jason Moffat, Holly Sassi, Michael Costanzo, Brenda J. Andrews
Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada
Dongqing Huang, Supipi Kaluarachchi, Dewald van Dyk, Helena Friesen, Richelle Sopko, Wei Ye, Nazareth Bastajian, Jason Moffat, Holly Sassi, Michael Costanzo, Brenda J. Andrews
Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: DH SK BJA. Performed the experiments: DH SK DvD HF RS NB JM MC. Contributed reagents/materials/analysis tools: HS. Wrote the paper: DH SK MC BJA. Edited the paper: HF. Provided technical assistance: WY.