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Research Article

Long-Term Relationships between Synaptic Tenacity, Synaptic Remodeling, and Network Activity

  • Amir Minerbi,

    Affiliations: Department of Physiology and Biophysics, Technion Faculty of Medicine, Haifa, Israel, Network Biology Research Laboratories, Lorry Lokey Interdisciplinary Center for Life Sciences and Engineering, Haifa, Israel, The Rappaport Family Institute for Research in the Medical Sciences, Haifa, Israel

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  • Roni Kahana,

    Affiliations: Department of Physiology and Biophysics, Technion Faculty of Medicine, Haifa, Israel, Network Biology Research Laboratories, Lorry Lokey Interdisciplinary Center for Life Sciences and Engineering, Haifa, Israel, The Rappaport Family Institute for Research in the Medical Sciences, Haifa, Israel

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  • Larissa Goldfeld,

    Affiliations: Department of Physiology and Biophysics, Technion Faculty of Medicine, Haifa, Israel, Network Biology Research Laboratories, Lorry Lokey Interdisciplinary Center for Life Sciences and Engineering, Haifa, Israel, The Rappaport Family Institute for Research in the Medical Sciences, Haifa, Israel

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  • Maya Kaufman,

    Affiliations: Department of Physiology and Biophysics, Technion Faculty of Medicine, Haifa, Israel, Network Biology Research Laboratories, Lorry Lokey Interdisciplinary Center for Life Sciences and Engineering, Haifa, Israel, The Rappaport Family Institute for Research in the Medical Sciences, Haifa, Israel

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  • Shimon Marom,

    Affiliations: Department of Physiology and Biophysics, Technion Faculty of Medicine, Haifa, Israel, Network Biology Research Laboratories, Lorry Lokey Interdisciplinary Center for Life Sciences and Engineering, Haifa, Israel

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  • Noam E. Ziv mail

    noamz@netvision.net.il

    Affiliations: Department of Physiology and Biophysics, Technion Faculty of Medicine, Haifa, Israel, Network Biology Research Laboratories, Lorry Lokey Interdisciplinary Center for Life Sciences and Engineering, Haifa, Israel, The Rappaport Family Institute for Research in the Medical Sciences, Haifa, Israel

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  • Published: June 23, 2009
  • DOI: 10.1371/journal.pbio.1000136

About the Authors

Amir Minerbi, Roni Kahana, Larissa Goldfeld, Maya Kaufman, Shimon Marom, Noam E. Ziv
Department of Physiology and Biophysics, Technion Faculty of Medicine, Haifa, Israel
Amir Minerbi, Roni Kahana, Larissa Goldfeld, Maya Kaufman, Shimon Marom, Noam E. Ziv
Network Biology Research Laboratories, Lorry Lokey Interdisciplinary Center for Life Sciences and Engineering, Haifa, Israel
Amir Minerbi, Roni Kahana, Larissa Goldfeld, Maya Kaufman, Noam E. Ziv
The Rappaport Family Institute for Research in the Medical Sciences, Haifa, Israel

Corresponding Author

Email: noamz@netvision.net.il

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: AM SM NEZ. Performed the experiments: AM RK LG. Analyzed the data: AM RK MK NEZ. Contributed reagents/materials/analysis tools: AM LG NEZ. Wrote the paper: AM NEZ.