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Research Article

Stochasticity in Protein Levels Drives Colinearity of Gene Order in Metabolic Operons of Escherichia coli

  • Károly Kovács,

    Affiliation: Institute of Biochemistry, Biological Research Center, Szeged, Hungary

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  • Laurence D. Hurst mail,

    L.D.Hurst@bath.ac.uk (LDH); pappb@brc.hu (BP)

    Affiliation: Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom

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  • Balázs Papp mail

    L.D.Hurst@bath.ac.uk (LDH); pappb@brc.hu (BP)

    Affiliation: Institute of Biochemistry, Biological Research Center, Szeged, Hungary

    X
  • Published: May 26, 2009
  • DOI: 10.1371/journal.pbio.1000115

About the Authors

Károly Kovács, Balázs Papp
Institute of Biochemistry, Biological Research Center, Szeged, Hungary
Laurence D. Hurst
Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: KK LDH BP. Performed the experiments: KK BP. Analyzed the data: KK LDH BP. Contributed reagents/materials/analysis tools: KK LDH BP. Wrote the paper: LDH BP.