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Research Article

Hotspots of Biased Nucleotide Substitutions in Human Genes

  • Jonas Berglund,

    Affiliation: Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden

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  • Katherine S Pollard,

    Affiliation: Gladstone Institutes, University of California, San Francisco, California, United States of America

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  • Matthew T Webster mail

    To whom correspondence should be addressed. E-mail: matthew.webster@imbim.uu.se

    Affiliation: Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden

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  • Published: January 27, 2009
  • DOI: 10.1371/journal.pbio.1000026

About the Authors

Jonas Berglund, Matthew T Webster
Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden
Katherine S Pollard
Gladstone Institutes, University of California, San Francisco, California, United States of America

Corresponding Author

Email: matthew.webster@imbim.uu.se

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

KSP and MTW conceived and designed the experiments. JB, KSP, and MTW performed the experiments and analyzed the data. KSP and MTW wrote the paper.