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Research Article

The NDR/LATS Family Kinase Cbk1 Directly Controls Transcriptional Asymmetry

  • Emily Mazanka,

    Affiliation: Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois, United States of America

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  • Jess Alexander,

    Affiliation: Department of Biology and Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Brian J Yeh,

    Affiliation: Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois, United States of America

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  • Patrick Charoenpong,

    Affiliation: Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois, United States of America

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  • Drew M Lowery,

    Affiliation: Department of Biology and Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Michael Yaffe,

    Affiliation: Department of Biology and Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Eric L Weiss mail

    To whom correspondence should be addressed. E-mail: elweiss@northwestern.edu

    Affiliation: Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois, United States of America

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  • Published: August 19, 2008
  • DOI: 10.1371/journal.pbio.0060203

About the Authors

Emily Mazanka, Brian J Yeh, Patrick Charoenpong, Eric L Weiss
Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois, United States of America
Jess Alexander, Drew M Lowery, Michael Yaffe
Department of Biology and Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Corresponding Author

Email: elweiss@northwestern.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

EM, JA, BJY, PC, DML, MY, and ELW conceived and designed the experiments. EM, JA, BJY, and PC performed the experiments. EM, JA, BJY, PC, and ELW analyzed the data. EM, JA, BJY, and ELW contributed reagents/materials/analysis tools. EM, BJY, and ELW wrote the paper.