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Research Article

Crystal Structure of the FeS Cluster–Containing Nucleotide Excision Repair Helicase XPD

  • Stefanie C Wolski equal contributor,

    equal contributor Contributed equally to this work with: Stefanie C Wolski, Jochen Kuper

    Affiliation: Rudolf Virchow Center for Experimental Biomedicine, Institute for Structural Biology, University of Würzburg, Würzburg, Germany

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  • Jochen Kuper equal contributor,

    equal contributor Contributed equally to this work with: Stefanie C Wolski, Jochen Kuper

    Affiliation: Rudolf Virchow Center for Experimental Biomedicine, Institute for Structural Biology, University of Würzburg, Würzburg, Germany

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  • Petra Hänzelmann,

    Affiliation: Rudolf Virchow Center for Experimental Biomedicine, Institute for Structural Biology, University of Würzburg, Würzburg, Germany

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  • James J Truglio,

    Affiliation: Department of Pharmacological Sciences, Stony Brook University, Stony Brook, New York, United States of America

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  • Deborah L Croteau,

    Affiliation: Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America

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  • Bennett Van Houten,

    Affiliation: Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America

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  • Caroline Kisker mail

    To whom correspondence should be addressed. E-mail: caroline.kisker@virchow.uni-wuerzburg.de

    Affiliation: Rudolf Virchow Center for Experimental Biomedicine, Institute for Structural Biology, University of Würzburg, Würzburg, Germany

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  • Published: June 24, 2008
  • DOI: 10.1371/journal.pbio.0060149

About the Authors

Stefanie C Wolski, Jochen Kuper, Petra Hänzelmann, Caroline Kisker
Rudolf Virchow Center for Experimental Biomedicine, Institute for Structural Biology, University of Würzburg, Würzburg, Germany
James J Truglio
Department of Pharmacological Sciences, Stony Brook University, Stony Brook, New York, United States of America
Deborah L Croteau, Bennett Van Houten
Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America

Corresponding Author

Email: caroline.kisker@virchow.uni-wuerzburg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SCW, JK, and CK conceived and designed the experiments. SCW, JK, PH, JJT, and DLC performed the experiments and analyzed the data. JK and CK wrote the manuscript. BVH helped write the manuscript and contributed important discussions and a figure to the manuscript.