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Research Article

Bergmann Glia and the Recognition Molecule CHL1 Organize GABAergic Axons and Direct Innervation of Purkinje Cell Dendrites

  • Fabrice Ango,

    Affiliations: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America, CNRS, UMR 5203, Institut de Génomique fonctionnelle, INSERM, U661, Montpellier, France, Université Montpellier 1 and 2, Montpellier, France

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  • Caizhi Wu,

    Affiliation: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

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  • Johannes J. Van der Want,

    Affiliation: Department of Cell Biology, Laboratory for Electron Microscopy, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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  • Priscilla Wu,

    Affiliation: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

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  • Melitta Schachner,

    Affiliations: Zentrum fur Molekulare Neurobiologie, Universitat Hamburg, Hamburg, Germany, Keck Center for Collaborative Neuroscience, Department of Cell Biology, Rutgers University, Piscataway, New Jersey, United States of America

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  • Z. Josh Huang mail

    To whom correspondence should be addressed. E-mail: huangj@cshl.edu

    Affiliation: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

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  • Published: April 29, 2008
  • DOI: 10.1371/journal.pbio.0060103

About the Authors

Fabrice Ango, Caizhi Wu, Priscilla Wu, Z. Josh Huang
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
Fabrice Ango
CNRS, UMR 5203, Institut de Génomique fonctionnelle, INSERM, U661, Montpellier, France
Fabrice Ango
Université Montpellier 1 and 2, Montpellier, France
Johannes J. Van der Want
Department of Cell Biology, Laboratory for Electron Microscopy, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Melitta Schachner
Zentrum fur Molekulare Neurobiologie, Universitat Hamburg, Hamburg, Germany
Melitta Schachner
Keck Center for Collaborative Neuroscience, Department of Cell Biology, Rutgers University, Piscataway, New Jersey, United States of America

Corresponding Author

Email: huangj@cshl.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

FA and ZJH conceived and organized the project, and designed the experiments. FA performed or contributed to all the experiments. JJVdW performed the electron microscopy experiments. CW and PW contributed to mice breeding and genotyping, and histology analysis. MS provided mutant mice and contributed to manuscript writing. FA and ZJH wrote the paper.