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Research Article

VirE2: A Unique ssDNA-Compacting Molecular Machine

  • Wilfried Grange equal contributor,

    equal contributor Contributed equally to this work with: Wilfried Grange, Myriam Duckely, Sudhir Husale

    Affiliations: Centre for Research on Adaptive Nanostructures and Nanodevices, Trinity College Dublin, Dublin, Ireland, National Centre of Competence in Research Nanoscale Science, Institute of Physics, Basel, Switzerland

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  • Myriam Duckely equal contributor,

    equal contributor Contributed equally to this work with: Wilfried Grange, Myriam Duckely, Sudhir Husale

    Affiliations: M. E. Müller Institute for Structural Biology, Basel, Switzerland, Novartis AG, Basel, Switzerland

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  • Sudhir Husale equal contributor,

    equal contributor Contributed equally to this work with: Wilfried Grange, Myriam Duckely, Sudhir Husale

    Affiliations: National Centre of Competence in Research Nanoscale Science, Institute of Physics, Basel, Switzerland, Rowland Institute at Harvard, Harvard University, Cambridge, Massachusetts, United States of America

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  • Susan Jacob,

    Affiliation: Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

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  • Andreas Engel,

    Affiliation: M. E. Müller Institute for Structural Biology, Basel, Switzerland

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  • Martin Hegner mail

    To whom correspondence should be addressed. E-mail: martin.hegner@tcd.ie

    Affiliations: Centre for Research on Adaptive Nanostructures and Nanodevices, Trinity College Dublin, Dublin, Ireland, National Centre of Competence in Research Nanoscale Science, Institute of Physics, Basel, Switzerland

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  • Published: February 26, 2008
  • DOI: 10.1371/journal.pbio.0060044

About the Authors

Wilfried Grange, Martin Hegner
Centre for Research on Adaptive Nanostructures and Nanodevices, Trinity College Dublin, Dublin, Ireland
Wilfried Grange, Sudhir Husale, Martin Hegner
National Centre of Competence in Research Nanoscale Science, Institute of Physics, Basel, Switzerland
Myriam Duckely, Andreas Engel
M. E. Müller Institute for Structural Biology, Basel, Switzerland
Myriam Duckely
Novartis AG, Basel, Switzerland
Sudhir Husale
Rowland Institute at Harvard, Harvard University, Cambridge, Massachusetts, United States of America
Susan Jacob
Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

Corresponding Author

Email: martin.hegner@tcd.ie

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

WG and MD conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, and wrote the paper. SH performed the experiments, analyzed the data, and contributed reagents/materials/analysis tools. SJ performed the experiments. AE and MH conceived and designed the experiments and wrote the paper.