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Research Article

A Ubiquitin Ligase Complex Regulates Caspase Activation During Sperm Differentiation in Drosophila

  • Eli Arama,

    Affiliations: Strang Laboratory of Cancer Research, The Rockefeller University, New York, New York, United States of America, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, United States of America

    ¤ Current address: Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

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  • Maya Bader,

    Affiliations: Strang Laboratory of Cancer Research, The Rockefeller University, New York, New York, United States of America, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, United States of America

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  • Gabrielle E Rieckhof,

    Affiliations: Strang Laboratory of Cancer Research, The Rockefeller University, New York, New York, United States of America, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, United States of America

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  • Hermann Steller mail

    To whom correspondence should be addressed. E-mail: steller@rockefeller.edu

    Affiliations: Strang Laboratory of Cancer Research, The Rockefeller University, New York, New York, United States of America, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, United States of America

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  • Published: September 18, 2007
  • DOI: 10.1371/journal.pbio.0050251

About the Authors

Eli Arama, Maya Bader, Gabrielle E Rieckhof, Hermann Steller
Strang Laboratory of Cancer Research, The Rockefeller University, New York, New York, United States of America
Eli Arama, Maya Bader, Gabrielle E Rieckhof, Hermann Steller
Howard Hughes Medical Institute, The Rockefeller University, New York, New York, United States of America

Corresponding Author

Email: steller@rockefeller.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

EA and HS conceived and designed the experiments, analyzed the data, and wrote the paper. EA performed the experiments, except for Fig. 10 which was designed and performed by MB. MB and GER participated in the genetic screens. MB helped with the experiments shown in Figs. 1I-J, 3D, 5, and S5.