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Research Article

BDCA2/FcεRIγ Complex Signals through a Novel BCR-Like Pathway in Human Plasmacytoid Dendritic Cells

  • Wei Cao mail,

    To whom correspondence should be addressed. E-mail: wcao@mdacc.tmc.edu (WC); yjliu@mdacc.tmc.edu (YJL).

    Affiliation: Department of Immunology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

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  • Li Zhang,

    Affiliation: Department of Biostatistics and Applied Mathematics, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

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  • David B Rosen,

    Affiliations: Department of Microbiology and Immunology, University of California at San Francisco, San Francisco, California, United States of America, Biomedical Sciences Graduate Program, University of California at San Francisco, San Francisco, California, United States of America, Cancer Research Institute, University of California at San Francisco, San Francisco, California, United States of America

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  • Laura Bover,

    Affiliation: Department of Immunology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

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  • Gokuran Watanabe,

    Affiliation: Department of Immunology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

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  • Musheng Bao,

    Affiliation: Department of Immunology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

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  • Lewis L Lanier,

    Affiliations: Department of Microbiology and Immunology, University of California at San Francisco, San Francisco, California, United States of America, Biomedical Sciences Graduate Program, University of California at San Francisco, San Francisco, California, United States of America, Cancer Research Institute, University of California at San Francisco, San Francisco, California, United States of America

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  • Yong-Jun Liu mail

    To whom correspondence should be addressed. E-mail: wcao@mdacc.tmc.edu (WC); yjliu@mdacc.tmc.edu (YJL).

    Affiliation: Department of Immunology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

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  • Published: September 11, 2007
  • DOI: 10.1371/journal.pbio.0050248

About the Authors

Wei Cao, Laura Bover, Gokuran Watanabe, Musheng Bao, Yong-Jun Liu
Department of Immunology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
Li Zhang
Department of Biostatistics and Applied Mathematics, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
David B Rosen, Lewis L Lanier
Department of Microbiology and Immunology, University of California at San Francisco, San Francisco, California, United States of America
David B Rosen, Lewis L Lanier
Biomedical Sciences Graduate Program, University of California at San Francisco, San Francisco, California, United States of America
David B Rosen, Lewis L Lanier
Cancer Research Institute, University of California at San Francisco, San Francisco, California, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

WC conceived, designed, and performed the experiments. LZ analyzed the data. DRB and GW performed some experiments. LB and MB prepared reagents. WC, LLL, and YJL had extensive scientific discussion for this study and wrote the paper.