Advertisement
Research Article

Different Quaternary Structures of Human RECQ1 Are Associated with Its Dual Enzymatic Activity

  • Laura Muzzolini,

    Affiliation: International Centre for Genetic Engineering and Biotechnology, Trieste, Italy

    X
  • Fabienne Beuron,

    Affiliation: Division of Molecular Biosciences, Faculty of Natural Sciences, Imperial College London, London, United Kingdom

    ¤a Current address: Structural Electron Microscopy, Section of Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, London, United Kingdom

    X
  • Ardan Patwardhan,

    Affiliation: Division of Molecular Biosciences, Faculty of Natural Sciences, Imperial College London, London, United Kingdom

    X
  • Venkateswarlu Popuri,

    Affiliation: International Centre for Genetic Engineering and Biotechnology, Trieste, Italy

    X
  • Sheng Cui,

    Affiliation: International Centre for Genetic Engineering and Biotechnology, Trieste, Italy

    ¤b Current address: Gene Center and Department of Chemistry and Biochemistry, University of Munich, Munich, Germany

    X
  • Benedetta Niccolini,

    Affiliation: International Centre for Genetic Engineering and Biotechnology, Trieste, Italy

    X
  • Mathieu Rappas,

    Affiliation: Division of Molecular Biosciences, Faculty of Natural Sciences, Imperial College London, London, United Kingdom

    X
  • Paul S Freemont,

    Affiliation: Division of Molecular Biosciences, Faculty of Natural Sciences, Imperial College London, London, United Kingdom

    X
  • Alessandro Vindigni mail

    To whom correspondence should be addressed. E-mail: vindigni@icgeb.org

    Affiliation: International Centre for Genetic Engineering and Biotechnology, Trieste, Italy

    X
  • Published: January 16, 2007
  • DOI: 10.1371/journal.pbio.0050020

About the Authors

Laura Muzzolini, Venkateswarlu Popuri, Sheng Cui, Benedetta Niccolini, Alessandro Vindigni
International Centre for Genetic Engineering and Biotechnology, Trieste, Italy
Fabienne Beuron, Ardan Patwardhan, Mathieu Rappas, Paul S Freemont
Division of Molecular Biosciences, Faculty of Natural Sciences, Imperial College London, London, United Kingdom

Corresponding Author

Email: vindigni@icgeb.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

LM, FB, PSF, and AV conceived and designed the experiments. LM, FB, VP, SC, BN, and MR performed the experiments. AP and AV analyzed the data. AV wrote the paper.