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Research Article

IAN Family Critically Regulates Survival and Development of T Lymphocytes

  • Takeshi Nitta,

    Affiliation: Division of Experimental Immunology, Institute for Genome Research, University of Tokushima, Tokushima, Japan

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  • Mariam Nasreen,

    Affiliation: Division of Experimental Immunology, Institute for Genome Research, University of Tokushima, Tokushima, Japan

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  • Takafumi Seike,

    Affiliation: Division of Experimental Immunology, Institute for Genome Research, University of Tokushima, Tokushima, Japan

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  • Atsushi Goji,

    Affiliation: Division of Experimental Immunology, Institute for Genome Research, University of Tokushima, Tokushima, Japan

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  • Izumi Ohigashi,

    Affiliation: Division of Experimental Immunology, Institute for Genome Research, University of Tokushima, Tokushima, Japan

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  • Tadaaki Miyazaki,

    Affiliation: Division of Molecular Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

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  • Tsutomu Ohta,

    Affiliation: Medical Genomics Center, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan

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  • Masamoto Kanno,

    Affiliation: Department of Immunology, Graduate School of Biomedical Sciences, Hiroshima University, Minami-ku, Hiroshima, Japan

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  • Yousuke Takahama mail

    To whom correspondence should be addressed. E-mail: takahama@genome.tokushima-u.ac.jp

    Affiliation: Division of Experimental Immunology, Institute for Genome Research, University of Tokushima, Tokushima, Japan

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  • Published: March 07, 2006
  • DOI: 10.1371/journal.pbio.0040103

About the Authors

Takeshi Nitta, Mariam Nasreen, Takafumi Seike, Atsushi Goji, Izumi Ohigashi, Yousuke Takahama
Division of Experimental Immunology, Institute for Genome Research, University of Tokushima, Tokushima, Japan
Tadaaki Miyazaki
Division of Molecular Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan
Tsutomu Ohta
Medical Genomics Center, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan
Masamoto Kanno
Department of Immunology, Graduate School of Biomedical Sciences, Hiroshima University, Minami-ku, Hiroshima, Japan

Corresponding Author

Email: takahama@genome.tokushima-u.ac.jp

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

TN and YT conceived and designed the experiments. TN, MN, TS, AG, and IO performed the experiments. TN, MN, and TS analyzed the data. TN, TM, TO, and MK contributed reagents/materials/analysis tools. TN and YT wrote the paper.