About the Authors
- Daniel A Kraut, Paul A Sigala, Daniel Herschlag
- Department of Biochemistry, Stanford University, Stanford, California, United States of America
- Brandon Pybus, Dagmar Ringe, Gregory A Petsko
- Department of Biochemistry, Brandeis University, Waltham, Massachusetts, United States of America
- Corey W Liu
- Stanford Magnetic Resonance Laboratory, Stanford University, Stanford, California, United States of America
The authors have declared that no competing interests exist.
DAK, PAS, and DH conceived and designed the experiments, BP performed X-ray crystallography experiments, PAS performed 1D 1H and 19F NMR experiments, PAS and CWL performed 2D NOESY NMR experiments, DAK carried out assay development and performed binding assays and ITC experiments. DAK, PAS, BP, CWL, DR, GAP, and DH analyzed the data. DAK, PAS, BP, CWL, DR, GAP, and DH wrote the paper.