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Research Article

A Transcriptional Profile of Aging in the Human Kidney

  • Graham E. J Rodwell,

    Affiliation: Division of Nephrology, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Rebecca Sonu,

    Affiliation: Department of Developmental Biology, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Jacob M Zahn,

    Affiliation: Department of Developmental Biology, Stanford University Medical Center, Stanford, California, United States of America

    X
  • James Lund,

    Affiliation: Department of Developmental Biology, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Julie Wilhelmy,

    Affiliation: Department of Biochemistry, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Lingli Wang,

    Affiliation: Department of Pathology, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Wenzhong Xiao,

    Affiliation: Department of Biochemistry, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Michael Mindrinos,

    Affiliation: Department of Biochemistry, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Emily Crane,

    Affiliation: Department of Developmental Biology, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Eran Segal,

    Affiliation: Department of Computer Science, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Bryan D Myers,

    Affiliation: Division of Nephrology, Stanford University Medical Center, Stanford, California, United States of America

    X
  • James D Brooks,

    Affiliation: Department of Urology, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Ronald W Davis,

    Affiliations: Department of Biochemistry, Stanford University Medical Center, Stanford, California, United States of America, Department of Genetics, Stanford University Medical Center, Stanford, California, United States of America

    X
  • John Higgins,

    Affiliation: Department of Pathology, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Art B Owen,

    Affiliation: Department of Statistics, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Stuart K Kim mail

    To whom correspondence should be addressed. E-mail: kim@cmgm.stanford.edu

    Affiliations: Department of Developmental Biology, Stanford University Medical Center, Stanford, California, United States of America, Department of Genetics, Stanford University Medical Center, Stanford, California, United States of America

    X
  • Published: November 30, 2004
  • DOI: 10.1371/journal.pbio.0020427

About the Authors

Graham E. J Rodwell, Bryan D Myers
Division of Nephrology, Stanford University Medical Center, Stanford, California, United States of America
Rebecca Sonu, Jacob M Zahn, James Lund, Emily Crane, Stuart K Kim
Department of Developmental Biology, Stanford University Medical Center, Stanford, California, United States of America
Julie Wilhelmy, Wenzhong Xiao, Michael Mindrinos, Ronald W Davis
Department of Biochemistry, Stanford University Medical Center, Stanford, California, United States of America
Lingli Wang, John Higgins
Department of Pathology, Stanford University Medical Center, Stanford, California, United States of America
Eran Segal
Department of Computer Science, Stanford University Medical Center, Stanford, California, United States of America
James D Brooks
Department of Urology, Stanford University Medical Center, Stanford, California, United States of America
Ronald W Davis, Stuart K Kim
Department of Genetics, Stanford University Medical Center, Stanford, California, United States of America
Art B Owen
Department of Statistics, Stanford University Medical Center, Stanford, California, United States of America

Corresponding Author

Email: kim@cmgm.stanford.edu

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

SKK conceived and designed the experiments. RS, JW, LW, EC, and JH performed the experiments. SKK, GEJR, JMZ, JL, WX, MM, ES, and ABO analyzed the data. MM, BDM, JDB, RWD and JH contributed reagents/materials/analysis tools. SKK, JMZ, and ABO wrote the paper.