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Research Article

Regulation of Muscle Fiber Type and Running Endurance by PPARδ

  • Yong-Xu Wang,

    Affiliation: Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America

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  • Chun-Li Zhang,

    Affiliation: Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America

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  • Ruth T Yu,

    Affiliation: Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America

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  • Helen K Cho,

    Affiliation: Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America

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  • Michael C Nelson,

    Affiliations: Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America, Howard Hughes Medical Institute, La Jolla, California, United States of America

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  • Corinne R Bayuga-Ocampo,

    Affiliation: Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America

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  • Jungyeob Ham,

    Affiliation: Marine Biotechnology Laboratory, School of Earth and Environmental Sciences, Seoul National University, Seoul, Korea

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  • Heonjoong Kang,

    Affiliation: Marine Biotechnology Laboratory, School of Earth and Environmental Sciences, Seoul National University, Seoul, Korea

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  • Ronald M Evans mail

    To whom correspondence should be addressed. E-mail: evans@salk.edu

    Affiliations: Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America, Howard Hughes Medical Institute, La Jolla, California, United States of America

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  • Published: August 24, 2004
  • DOI: 10.1371/journal.pbio.0020294

About the Authors

Yong-Xu Wang, Chun-Li Zhang, Ruth T Yu, Helen K Cho, Michael C Nelson, Corinne R Bayuga-Ocampo, Ronald M Evans
Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America
Michael C Nelson, Ronald M Evans
Howard Hughes Medical Institute, La Jolla, California, United States of America
Jungyeob Ham, Heonjoong Kang
Marine Biotechnology Laboratory, School of Earth and Environmental Sciences, Seoul National University, Seoul, Korea

Corresponding Author

Email: evans@salk.edu

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

YXW and RME conceived and designed the experiments. YXW, CLZ, RTY, MCN, and CRBO performed the experiments. YXW, CLZ, and RME analyzed the data. HKC, JH, and HK contributed reagents/materials/analysis tools. YXW and RME wrote the paper.