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Research Article

A Chromosomal Memory Triggered by Xist Regulates Histone Methylation in X Inactivation

  • Alexander Kohlmaier,

    Affiliation: Research Institute of Molecular Pathology, Vienna, Austria

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  • Fabio Savarese,

    Affiliation: Research Institute of Molecular Pathology, Vienna, Austria

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  • Monika Lachner,

    Affiliation: Research Institute of Molecular Pathology, Vienna, Austria

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  • Joost Martens,

    Affiliation: Research Institute of Molecular Pathology, Vienna, Austria

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  • Thomas Jenuwein,

    Affiliation: Research Institute of Molecular Pathology, Vienna, Austria

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  • Anton Wutz mail

    To whom correspondence should be addressed. E-mail: wutz@imp.univie.ac.at

    Affiliation: Research Institute of Molecular Pathology, Vienna, Austria

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  • Published: July 13, 2004
  • DOI: 10.1371/journal.pbio.0020171

About the Authors

Alexander Kohlmaier, Fabio Savarese, Monika Lachner, Joost Martens, Thomas Jenuwein, Anton Wutz
Research Institute of Molecular Pathology, Vienna, Austria

Corresponding Author

Email: wutz@imp.univie.ac.at

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

AK, FS, ML, JM, TJ, and AW conceived and designed the experiments. AK, FS, ML, JM, and AW performed the experiments. AK, FS, ML, JM, and AW analyzed the data. AK, TJ, and AW contributed reagents/materials/analysis tools. AK, TJ, and AW wrote the paper.