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Research Article

Activation of Arp2/3 Complex: Addition of the First Subunit of the New Filament by a WASP Protein Triggers Rapid ATP Hydrolysis on Arp2

  • Mark J Dayel,

    Affiliation: Graduate Group in Biophysics, University of California, San Francisco, San Francisco, California, United States of America

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  • R. Dyche Mullins mail

    To whom correspondence should be addressed. E-mail: dyche@mullinslab.ucsf.edu

    Affiliation: Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California, United States of America

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  • Published: April 13, 2004
  • DOI: 10.1371/journal.pbio.0020091

About the Authors

Mark J Dayel
Graduate Group in Biophysics, University of California, San Francisco, San Francisco, California, United States of America
R. Dyche Mullins
Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California, United States of America

Corresponding Author

Email: dyche@mullinslab.ucsf.edu

Author Contributions

MJD and RDM conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, and wrote the paper.