Advertisement
Research Article

A Spontaneous, Recurrent Mutation in Divalent Metal Transporter-1 Exposes a Calcium Entry Pathway

  • Haoxing Xu equal contributor,

    equal contributor Contributed equally to this work with: Haoxing Xu, Jie Jin

    Affiliation: Howard Hughes Medical Institute, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Jie Jin equal contributor,

    equal contributor Contributed equally to this work with: Haoxing Xu, Jie Jin

    Affiliation: Howard Hughes Medical Institute, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Louis J DeFelice,

    Affiliation: Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

    X
  • Nancy C Andrews mail,

    To whom correspondence should be addressed. E-mail: nandrews@enders.tch.harvard.edu (NA), Email: dclapham@enders.tch.harvard.edu (DC)

    Affiliation: Howard Hughes Medical Institute, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • David E Clapham mail

    To whom correspondence should be addressed. E-mail: nandrews@enders.tch.harvard.edu (NA), Email: dclapham@enders.tch.harvard.edu (DC)

    Affiliation: Howard Hughes Medical Institute, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Published: March 16, 2004
  • DOI: 10.1371/journal.pbio.0020050

About the Authors

Haoxing Xu, Jie Jin, Nancy C Andrews, David E Clapham
Howard Hughes Medical Institute, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
Louis J DeFelice
Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

HX, JJ, LJD, NCA, and DEC conceived and designed the experiments. HX and JJ performed the experiments. HX and JJ analyzed the data. HX, NCA, and DEC wrote the paper.